KCNB1

potassium voltage-gated channel subfamily B member 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2 Human YES

GO terms:

Biological Process:
action potential [GO:0001508],
vesicle docking involved in exocytosis [GO:0006904],
glutamate receptor signaling pathway [GO:0007215],
positive regulation of norepinephrine secretion [GO:0010701],
cellular response to nutrient levels [GO:0031669],
positive regulation of catecholamine secretion [GO:0033605],
regulation of ion transmembrane transport [GO:0034765],
glucose homeostasis [GO:0042593],
positive regulation of calcium ion-dependent exocytosis [GO:0045956],
negative regulation of insulin secretion [GO:0046676],
regulation of insulin secretion [GO:0050796],
protein homooligomerization [GO:0051260],
cellular response to glucose stimulus [GO:0071333],
potassium ion transmembrane transport [GO:0071805],
protein localization to plasma membrane [GO:0072659],
positive regulation of protein targeting to membrane [GO:0090314],
regulation of action potential [GO:0098900],
positive regulation of long term synaptic depression [GO:1900454],
regulation of motor neuron apoptotic process [GO:2000671],
ion transport [GO:0006811],
potassium ion transport [GO:0006813],
exocytosis [GO:0006887],
transmembrane transport [GO:0055085],
potassium ion export across plasma membrane [GO:0097623],

Molecular Function:
voltage-gated potassium channel activity [GO:0005249],
delayed rectifier potassium channel activity [GO:0005251],
protein binding [GO:0005515],
ion channel binding [GO:0044325],
protein heterodimerization activity [GO:0046982],
SNARE binding [GO:0000149],
ion channel activity [GO:0005216],
voltage-gated ion channel activity [GO:0005244],
potassium channel activity [GO:0005267],
outward rectifier potassium channel activity [GO:0015271],
protein N-terminus binding [GO:0047485],

Cellular Component:
plasma membrane [GO:0005886],
voltage-gated potassium channel complex [GO:0008076],
integral component of membrane [GO:0016021],
lateral plasma membrane [GO:0016328],
axon [GO:0030424],
dendrite [GO:0030425],
dendrite membrane [GO:0032590],
neuronal cell body membrane [GO:0032809],
sarcolemma [GO:0042383],
perikaryon [GO:0043204],
postsynaptic membrane [GO:0045211],
endoplasmic reticulum [GO:0005783],
cell surface [GO:0009986],
membrane [GO:0016020],
cell junction [GO:0030054],
cell projection [GO:0042995],
neuron projection [GO:0043005],
neuronal cell body [GO:0043025],
synapse [GO:0045202],