APOBEC3B
apolipoprotein B mRNA editing enzyme catalytic subunit 3B
Link to human orthologSearch for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 27545311 | U2OS | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 27323328 | Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni | Human | YES | |
| 29548335 | Saos-2 | Human | YES | |
| 30987592 | MCF7 | Breast | Human | YES |
| 30988157 | IMR-90 | Human | YES | |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
GO terms:
Biological Process:
cytidine deamination [GO:0009972],
negative regulation of transposition [GO:0010529],
cytidine to uridine editing [GO:0016554],
innate immune response [GO:0045087],
negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869],
defense response to virus [GO:0051607],
DNA cytosine deamination [GO:0070383],
DNA demethylation [GO:0080111],
Molecular Function:
RNA binding [GO:0003723],
cytidine deaminase activity [GO:0004126],
protein binding [GO:0005515],
zinc ion binding [GO:0008270],
deoxycytidine deaminase activity [GO:0047844],
Cellular Component:
cytoplasmic mRNA processing body [GO:0000932],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],