apolipoprotein B mRNA editing enzyme catalytic subunit 3B

Link to human ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
27545311 U2OS Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
27323328 Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni Human YES
29548335 Saos-2 Human YES
30987592 MCF7 Breast Human YES
30988157 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
cytidine deamination [GO:0009972],
negative regulation of transposition [GO:0010529],
cytidine to uridine editing [GO:0016554],
innate immune response [GO:0045087],
negative regulation of single stranded viral RNA replication via double stranded DNA intermediate [GO:0045869],
defense response to virus [GO:0051607],
DNA cytosine deamination [GO:0070383],
DNA demethylation [GO:0080111],

Molecular Function:
RNA binding [GO:0003723],
cytidine deaminase activity [GO:0004126],
protein binding [GO:0005515],
zinc ion binding [GO:0008270],
deoxycytidine deaminase activity [GO:0047844],

Cellular Component:
cytoplasmic mRNA processing body [GO:0000932],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],