APLP2
amyloid beta precursor like protein 2
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 28844647 | BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 | Skin, Lung | Human | YES |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
| 31983656 | MSC | Human | YES | |
GO terms:
Biological Process:
platelet degranulation [GO:0002576],
G-protein coupled receptor signaling pathway [GO:0007186],
negative regulation of endopeptidase activity [GO:0010951],
post-translational protein modification [GO:0043687],
cellular protein metabolic process [GO:0044267],
suckling behavior [GO:0001967],
cellular copper ion homeostasis [GO:0006878],
regulation of epidermal growth factor-activated receptor activity [GO:0007176],
mating behavior [GO:0007617],
locomotory behavior [GO:0007626],
cholesterol metabolic process [GO:0008203],
embryo development [GO:0009790],
extracellular matrix organization [GO:0030198],
forebrain development [GO:0030900],
midbrain development [GO:0030901],
regulation of protein binding [GO:0043393],
neuromuscular process controlling balance [GO:0050885],
Molecular Function:
DNA binding [GO:0003677],
serine-type endopeptidase inhibitor activity [GO:0004867],
protein binding [GO:0005515],
heparin binding [GO:0008201],
identical protein binding [GO:0042802],
transition metal ion binding [GO:0046914],
metal ion binding [GO:0046872],
Cellular Component:
nucleus [GO:0005634],
endoplasmic reticulum lumen [GO:0005788],
plasma membrane [GO:0005886],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
platelet alpha granule membrane [GO:0031092],
extracellular exosome [GO:0070062],