ITGA7

integrin subunit alpha 7

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2 Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
cell-matrix adhesion [GO:0007160],
integrin-mediated signaling pathway [GO:0007229],
muscle organ development [GO:0007517],
regulation of cell shape [GO:0008360],
extracellular matrix organization [GO:0030198],
heterotypic cell-cell adhesion [GO:0034113],
endodermal cell differentiation [GO:0035987],
cell adhesion [GO:0007155],
cell migration [GO:0016477],
blood vessel morphogenesis [GO:0048514],

Molecular Function:
protein binding [GO:0005515],
metal ion binding [GO:0046872],
integrin binding [GO:0005178],
laminin binding [GO:0043236],
macromolecular complex binding [GO:0044877],
cell adhesion molecule binding [GO:0050839],

Cellular Component:
plasma membrane [GO:0005886],
integrin complex [GO:0008305],
cell surface [GO:0009986],
cytoplasm [GO:0005737],
muscle tendon junction [GO:0005927],
membrane [GO:0016020],
integral component of membrane [GO:0016021],
neuromuscular junction [GO:0031594],
integrin alpha7-beta1 complex [GO:0034677],
sarcolemma [GO:0042383],