APLP1
amyloid beta precursor like protein 1
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 27323328 | Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni | Human | YES | |
| 28844647 | BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 | Skin, Lung | Human | YES |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
| 29548335 | Saos-2, Li-Fraumeni | Human | YES | |
| 31148378 | MRC-5 | Human | YES | |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
GO terms:
Biological Process:
endocytosis [GO:0006897],
apoptotic process [GO:0006915],
cell adhesion [GO:0007155],
nervous system development [GO:0007399],
animal organ morphogenesis [GO:0009887],
cellular response to norepinephrine stimulus [GO:0071874],
mRNA polyadenylation [GO:0006378],
regulation of translation [GO:0006417],
extracellular matrix organization [GO:0030198],
forebrain development [GO:0030900],
Molecular Function:
protein binding [GO:0005515],
heparin binding [GO:0008201],
alpha-2A adrenergic receptor binding [GO:0031694],
alpha-2B adrenergic receptor binding [GO:0031695],
alpha-2C adrenergic receptor binding [GO:0031696],
identical protein binding [GO:0042802],
transition metal ion binding [GO:0046914],
metal ion binding [GO:0046872],
Cellular Component:
basement membrane [GO:0005604],
plasma membrane [GO:0005886],
integral component of membrane [GO:0016021],
perinuclear region of cytoplasm [GO:0048471],
cytoplasm [GO:0005737],
Golgi apparatus [GO:0005794],
membrane [GO:0016020],