APAF1 interacting protein

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
apoptotic process [GO:0006915],
L-methionine biosynthetic process from S-adenosylmethionine [GO:0019284],
L-methionine biosynthetic process from methylthioadenosine [GO:0019509],
negative regulation of apoptotic process [GO:0043066],
protein homotetramerization [GO:0051289],
pyroptosis [GO:0070269],
regulation of ERK1 and ERK2 cascade [GO:0070372],
cellular amino acid biosynthetic process [GO:0008652],
methionine biosynthetic process [GO:0009086],

Molecular Function:
protein binding [GO:0005515],
zinc ion binding [GO:0008270],
identical protein binding [GO:0042802],
methylthioribulose 1-phosphate dehydratase activity [GO:0046570],
lyase activity [GO:0016829],
metal ion binding [GO:0046872],

Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],