API5

apoptosis inhibitor 5

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
apoptotic process [GO:0006915],
negative regulation of apoptotic process [GO:0043066],
negative regulation of fibroblast apoptotic process [GO:2000270],

Molecular Function:
RNA binding [GO:0003723],
protein binding [GO:0005515],
fibroblast growth factor binding [GO:0017134],

Cellular Component:
nucleus [GO:0005634],
spliceosomal complex [GO:0005681],
cytoplasm [GO:0005737],
membrane [GO:0016020],
nuclear speck [GO:0016607],