APBB2

amyloid beta precursor protein binding family B member 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
neuron migration [GO:0001764],
regulation of transcription, DNA-templated [GO:0006355],
cell cycle arrest [GO:0007050],
axon guidance [GO:0007411],
extracellular matrix organization [GO:0030198],
negative regulation of cell growth [GO:0030308],
intracellular signal transduction [GO:0035556],
positive regulation of apoptotic process [GO:0043065],
negative regulation of apoptotic process [GO:0043066],
actin filament-based movement [GO:0030048],
protein stabilization [GO:0050821],

Molecular Function:
beta-amyloid binding [GO:0001540],
protein binding [GO:0005515],
transcription factor binding [GO:0008134],
histone acetyltransferase binding [GO:0035035],

Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
membrane [GO:0016020],
lamellipodium [GO:0030027],
growth cone [GO:0030426],
synapse [GO:0045202],