APBA1

amyloid beta precursor protein binding family A member 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2, Li-Fraumeni Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
in utero embryonic development [GO:0001701],
intracellular protein transport [GO:0006886],
cell adhesion [GO:0007155],
chemical synaptic transmission [GO:0007268],
neurotransmitter secretion [GO:0007269],
nervous system development [GO:0007399],
locomotory behavior [GO:0007626],
axo-dendritic transport [GO:0008088],
regulation of gene expression [GO:0010468],
glutamate secretion [GO:0014047],
gamma-aminobutyric acid secretion [GO:0014051],
multicellular organism growth [GO:0035264],
macromolecular complex assembly [GO:0065003],
regulation of synaptic vesicle exocytosis [GO:2000300],
protein transport [GO:0015031],

Molecular Function:
beta-amyloid binding [GO:0001540],
protein binding [GO:0005515],
phosphatidylinositol-4,5-bisphosphate binding [GO:0005546],
PDZ domain binding [GO:0030165],
macromolecular complex binding [GO:0044877],

Cellular Component:
nucleus [GO:0005634],
cytoplasm [GO:0005737],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
synaptic vesicle [GO:0008021],
dendritic spine [GO:0043197],
synapse [GO:0045202],
perinuclear region of cytoplasm [GO:0048471],
presynaptic active zone membrane [GO:0048787],
glutamatergic synapse [GO:0098978],
membrane [GO:0016020],
macromolecular complex [GO:0032991],