AP2M1

adaptor related protein complex 2 subunit mu 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
intracellular protein transport [GO:0006886],
endocytosis [GO:0006897],
membrane budding [GO:0006900],
vesicle-mediated transport [GO:0016192],
antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886],
receptor internalization [GO:0031623],
low-density lipoprotein particle receptor catabolic process [GO:0032802],
low-density lipoprotein particle clearance [GO:0034383],
cellular macromolecular complex assembly [GO:0034622],
ephrin receptor signaling pathway [GO:0048013],
regulation of defense response to virus by virus [GO:0050690],
Wnt signaling pathway, planar cell polarity pathway [GO:0060071],
membrane organization [GO:0061024],
clathrin-dependent endocytosis [GO:0072583],
regulation of vesicle size [GO:0097494],
negative regulation of protein localization to plasma membrane [GO:1903077],
positive regulation of receptor internalization [GO:0002092],
protein transport [GO:0015031],
synaptic vesicle endocytosis [GO:0048488],
macromolecular complex assembly [GO:0065003],
postsynaptic neurotransmitter receptor internalization [GO:0098884],
positive regulation of synaptic vesicle endocytosis [GO:1900244],

Molecular Function:
signal sequence binding [GO:0005048],
protein binding [GO:0005515],
lipid binding [GO:0008289],
clathrin adaptor activity [GO:0035615],
ion channel binding [GO:0044325],
low-density lipoprotein particle receptor binding [GO:0050750],
disordered domain specific binding [GO:0097718],

Cellular Component:
lysosomal membrane [GO:0005765],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
clathrin-coated pit [GO:0005905],
AP-2 adaptor complex [GO:0030122],
endocytic vesicle membrane [GO:0030666],
clathrin-coated endocytic vesicle membrane [GO:0030669],
cytoplasmic vesicle [GO:0031410],
endolysosome membrane [GO:0036020],
intracellular membrane-bounded organelle [GO:0043231],
clathrin-coated endocytic vesicle [GO:0045334],
extracellular exosome [GO:0070062],
mitochondrion [GO:0005739],
membrane [GO:0016020],
clathrin adaptor complex [GO:0030131],
secretory granule [GO:0030141],
glutamatergic synapse [GO:0098978],