AP1S1

adaptor related protein complex 1 subunit sigma 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
intracellular protein transport [GO:0006886],
receptor-mediated endocytosis [GO:0006898],
response to virus [GO:0009615],
vesicle-mediated transport [GO:0016192],
antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886],
retrograde transport, endosome to Golgi [GO:0042147],
regulation of defense response to virus by virus [GO:0050690],
protein transport [GO:0015031],

Molecular Function:
protein binding [GO:0005515],

Cellular Component:
Golgi membrane [GO:0000139],
lysosomal membrane [GO:0005765],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
clathrin-coated pit [GO:0005905],
membrane [GO:0016020],
AP-1 adaptor complex [GO:0030121],
cytoplasmic vesicle membrane [GO:0030659],
trans-Golgi network membrane [GO:0032588],
terminal bouton [GO:0043195],
intracellular membrane-bounded organelle [GO:0043231],
trans-Golgi network [GO:0005802],
membrane coat [GO:0030117],
cytoplasmic vesicle [GO:0031410],