adaptor related protein complex 1 associated regulatory protein

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
negative regulation of receptor recycling [GO:0001920],
protein transport [GO:0015031],
regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315],
cellular protein localization [GO:0034613],
vesicle targeting, trans-Golgi to endosome [GO:0048203],
negative regulation of substrate adhesion-dependent cell spreading [GO:1900025],
negative regulation of cell motility [GO:2000146],

Molecular Function:
kinesin binding [GO:0019894],
AP-1 adaptor complex binding [GO:0035650],
Arp2/3 complex binding [GO:0071933],

Cellular Component:
endosome [GO:0005768],
early endosome [GO:0005769],
late endosome [GO:0005770],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
transport vesicle [GO:0030133],