AOX1
aldehyde oxidase 1
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29548335 | Saos-2, Li-Fraumeni | Human | YES | |
| 30626320 | HBEC | Human | NO | |
| 30987592 | MCF7 | Breast | Human | YES |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
| 32109515 | Brain | Mouse | NO | |
GO terms:
Biological Process:
xanthine catabolic process [GO:0009115],
drug metabolic process [GO:0017144],
electron transport chain [GO:0022900],
vitamin B6 metabolic process [GO:0042816],
oxidation-reduction process [GO:0055114],
Molecular Function:
aldehyde oxidase activity [GO:0004031],
xanthine dehydrogenase activity [GO:0004854],
iron ion binding [GO:0005506],
electron carrier activity [GO:0009055],
identical protein binding [GO:0042802],
protein homodimerization activity [GO:0042803],
molybdopterin cofactor binding [GO:0043546],
flavin adenine dinucleotide binding [GO:0050660],
NAD binding [GO:0051287],
2 iron, 2 sulfur cluster binding [GO:0051537],
FAD binding [GO:0071949],
oxidoreductase activity [GO:0016491],
metal ion binding [GO:0046872],
retinal oxidase activity [GO:0050250],
iron-sulfur cluster binding [GO:0051536],
Cellular Component:
cytosol [GO:0005829],
extracellular exosome [GO:0070062],
cytoplasm [GO:0005737],