AOC3

amine oxidase copper containing 3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

GO terms:

Biological Process:
xenobiotic metabolic process [GO:0006805],
inflammatory response [GO:0006954],
cell adhesion [GO:0007155],
amine metabolic process [GO:0009308],
response to antibiotic [GO:0046677],
oxidation-reduction process [GO:0055114],
negative regulation of primary amine oxidase activity [GO:1902283],
leukocyte migration involved in inflammatory response [GO:0002523],
positive regulation of acute inflammatory response [GO:0002675],
positive regulation of leukocyte migration [GO:0002687],
regulation of blood pressure [GO:0008217],
positive regulation of glucose transport [GO:0010828],
response to immobilization stress [GO:0035902],
eating behavior [GO:0042755],

Molecular Function:
copper ion binding [GO:0005507],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
primary amine oxidase activity [GO:0008131],
identical protein binding [GO:0042802],
protein heterodimerization activity [GO:0046982],
quinone binding [GO:0048038],
tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593],
aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594],
aliphatic-amine oxidase activity [GO:0052595],
phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596],
oxidoreductase activity [GO:0016491],
metal ion binding [GO:0046872],

Cellular Component:
cytoplasm [GO:0005737],
early endosome [GO:0005769],
endoplasmic reticulum [GO:0005783],
Golgi apparatus [GO:0005794],
plasma membrane [GO:0005886],
microvillus [GO:0005902],
cell surface [GO:0009986],
integral component of membrane [GO:0016021],
extracellular space [GO:0005615],
membrane [GO:0016020],
intracellular membrane-bounded organelle [GO:0043231],