IFT88

intraflagellar transport 88

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES

GO terms:

Biological Process:
kidney development [GO:0001822],
intraciliary transport involved in cilium assembly [GO:0035735],
intraciliary transport [GO:0042073],
inner ear receptor stereocilium organization [GO:0060122],
cilium assembly [GO:0060271],
regulation of cilium assembly [GO:1902017],
non-motile cilium assembly [GO:1905515],
regulation of autophagosome assembly [GO:2000785],
eye development [GO:0001654],
endothelial cell morphogenesis [GO:0001886],
liver development [GO:0001889],
cilium movement [GO:0003341],
Notch signaling pathway [GO:0007219],
smoothened signaling pathway [GO:0007224],
sperm axoneme assembly [GO:0007288],
spermatid nucleus elongation [GO:0007290],
determination of left/right symmetry [GO:0007368],
nervous system development [GO:0007399],
brain development [GO:0007420],
heart development [GO:0007507],
protein localization [GO:0008104],
epidermis development [GO:0008544],
animal organ morphogenesis [GO:0009887],
anterior/posterior pattern specification [GO:0009952],
dorsal/ventral pattern formation [GO:0009953],
spinal cord dorsal/ventral patterning [GO:0021513],
telencephalon development [GO:0021537],
cell projection organization [GO:0030030],
lung development [GO:0030324],
forebrain development [GO:0030900],
pancreas development [GO:0031016],
cytoplasmic microtubule organization [GO:0031122],
response to fluid shear stress [GO:0034405],
epidermal stem cell homeostasis [GO:0036334],
regulation of odontogenesis of dentin-containing tooth [GO:0042487],
embryonic digit morphogenesis [GO:0042733],
positive regulation of insulin-like growth factor receptor signaling pathway [GO:0043568],
regulation of fat cell differentiation [GO:0045598],
forebrain morphogenesis [GO:0048853],
negative regulation of epithelial cell proliferation [GO:0050680],
cardiac muscle cell differentiation [GO:0055007],
limb development [GO:0060173],
regulation of feeding behavior [GO:0060259],
cardiac septum morphogenesis [GO:0060411],
lung vasculature development [GO:0060426],
heart formation [GO:0060914],
neural precursor cell proliferation [GO:0061351],
regulation of protein processing [GO:0070613],
cochlea development [GO:0090102],
primary palate development [GO:1903929],

Molecular Function:
protein binding [GO:0005515],
kinesin binding [GO:0019894],

Cellular Component:
cytoplasm [GO:0005737],
centrosome [GO:0005813],
centriole [GO:0005814],
cilium [GO:0005929],
intraciliary transport particle B [GO:0030992],
motile cilium [GO:0031514],
ciliary basal body [GO:0036064],
sperm flagellum [GO:0036126],
ciliary tip [GO:0097542],
ciliary base [GO:0097546],
non-motile cilium [GO:0097730],
acrosomal membrane [GO:0002080],
outer acrosomal membrane [GO:0002081],
trans-Golgi network [GO:0005802],
cytoskeleton [GO:0005856],
axoneme [GO:0005930],
photoreceptor connecting cilium [GO:0032391],
cell projection [GO:0042995],
kinocilium [GO:0060091],
axonemal basal plate [GO:0097541],