ANXA6

annexin A6

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
neural crest cell migration [GO:0001755],
plasma membrane repair [GO:0001778],
growth plate cartilage chondrocyte differentiation [GO:0003418],
regulation of muscle contraction [GO:0006937],
ion transmembrane transport [GO:0034220],
negative regulation of sequestering of calcium ion [GO:0051283],
mitochondrial calcium ion homeostasis [GO:0051560],
calcium ion transmembrane transport [GO:0070588],
apoptotic signaling pathway [GO:0097190],
calcium ion transport [GO:0006816],

Molecular Function:
phosphatidylserine binding [GO:0001786],
calcium channel activity [GO:0005262],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
GTP binding [GO:0005525],
calcium-dependent phospholipid binding [GO:0005544],
lipid binding [GO:0008289],
ligand-gated ion channel activity [GO:0015276],
cholesterol binding [GO:0015485],
chondroitin sulfate binding [GO:0035374],
identical protein binding [GO:0042802],
calcium-dependent protein binding [GO:0048306],
actin filament binding [GO:0051015],
macromolecular complex binding [GO:0044877],

Cellular Component:
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
lysosomal membrane [GO:0005765],
focal adhesion [GO:0005925],
membrane [GO:0016020],
late endosome membrane [GO:0031902],
melanosome [GO:0042470],
perinuclear region of cytoplasm [GO:0048471],
extracellular exosome [GO:0070062],
nucleus [GO:0005634],
cytosol [GO:0005829],
intercalated disc [GO:0014704],
apical plasma membrane [GO:0016324],
macromolecular complex [GO:0032991],
sarcolemma [GO:0042383],