annexin A3

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2, Li-Fraumeni Human YES
30987592 MCF7 Breast Human YES
31945054 IMR-90 Human YES
31945125 Primary astrocytes derived from brain Human YES
31971661 Primary mesenchymal stem cells derived from adipose tissue Mouse YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
31915373 Hheart_LA_VS healthy Cardiomyocyte,Endothelial cell Human NO
31915373 Hheart_LV_VS healthy Endothelial cell Human NO

GO terms:

Biological Process:
phagocytosis [GO:0006909],
positive regulation of endothelial cell migration [GO:0010595],
hippocampus development [GO:0021766],
animal organ regeneration [GO:0031100],
defense response to bacterium [GO:0042742],
negative regulation of catalytic activity [GO:0043086],
neutrophil degranulation [GO:0043312],
positive regulation of angiogenesis [GO:0045766],
positive regulation of DNA metabolic process [GO:0051054],
positive regulation of sequence-specific DNA binding transcription factor activity [GO:0051091],
response to glucocorticoid [GO:0051384],
response to growth factor [GO:0070848],

Molecular Function:
calcium ion binding [GO:0005509],
calcium-dependent phospholipid binding [GO:0005544],
phospholipase A2 inhibitor activity [GO:0019834],
calcium-dependent protein binding [GO:0048306],
phospholipase inhibitor activity [GO:0004859],

Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
membrane [GO:0016020],
axon [GO:0030424],
dendrite [GO:0030425],
phagocytic vesicle membrane [GO:0030670],
specific granule [GO:0042581],
neuronal cell body [GO:0043025],
extracellular exosome [GO:0070062],