IDI1

isopentenyl-diphosphate delta isomerase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31148378 MRC-5 Human YES
32029712 Primary synovial fibroblast Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31534052 Kidney Mouse YES
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
cholesterol biosynthetic process [GO:0006695],
isopentenyl diphosphate biosynthetic process [GO:0009240],
regulation of cholesterol biosynthetic process [GO:0045540],
dimethylallyl diphosphate biosynthetic process [GO:0050992],
isoprenoid biosynthetic process [GO:0008299],
response to stilbenoid [GO:0035634],

Molecular Function:
isopentenyl-diphosphate delta-isomerase activity [GO:0004452],
hydrolase activity [GO:0016787],
metal ion binding [GO:0046872],
magnesium ion binding [GO:0000287],
manganese ion binding [GO:0030145],

Cellular Component:
cytoplasm [GO:0005737],
peroxisome [GO:0005777],
cytosol [GO:0005829],
mitochondrion [GO:0005739],