isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945054 IMR-90 Human YES

GO terms:

Biological Process:
tricarboxylic acid cycle [GO:0006099],
isocitrate metabolic process [GO:0006102],
electron transport chain [GO:0022900],
2-oxoglutarate metabolic process [GO:0006103],
NADH metabolic process [GO:0006734],

Molecular Function:
magnesium ion binding [GO:0000287],
isocitrate dehydrogenase (NAD+) activity [GO:0004449],
electron carrier activity [GO:0009055],
NAD binding [GO:0051287],

Cellular Component:
nucleus [GO:0005634],
mitochondrion [GO:0005739],
mitochondrial matrix [GO:0005759],