ABCG2

ATP binding cassette subfamily G member 2 (Junior blood group)

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

GO terms:

Biological Process:
cellular iron ion homeostasis [GO:0006879],
urate transport [GO:0015747],
biotin transport [GO:0015878],
riboflavin transport [GO:0032218],
urate metabolic process [GO:0046415],
transmembrane transport [GO:0055085],
transepithelial transport [GO:0070633],
cellular detoxification [GO:1990748],
drug transport across blood-brain barrier [GO:1990962],
glucuronoside metabolic process [GO:0019389],
embryonic process involved in female pregnancy [GO:0060136],
macromolecular complex assembly [GO:0065003],
negative regulation of intestinal absorption [GO:1904479],
drug transmembrane export [GO:1990961],

Molecular Function:
protein binding [GO:0005515],
ATP binding [GO:0005524],
xenobiotic-transporting ATPase activity [GO:0008559],
urate transmembrane transporter activity [GO:0015143],
biotin transporter activity [GO:0015225],
efflux transmembrane transporter activity [GO:0015562],
ATPase activity [GO:0016887],
riboflavin transporter activity [GO:0032217],
ATPase activity, coupled to transmembrane movement of substances [GO:0042626],
identical protein binding [GO:0042802],
protein homodimerization activity [GO:0042803],
xenobiotic transporter activity [GO:0042910],
nucleotide binding [GO:0000166],
cytoskeletal protein binding [GO:0008092],
amide transmembrane transporter activity [GO:0042887],

Cellular Component:
nucleoplasm [GO:0005654],
plasma membrane [GO:0005886],
integral component of membrane [GO:0016021],
apical plasma membrane [GO:0016324],
brush border membrane [GO:0031526],
mitochondrial membrane [GO:0031966],
membrane raft [GO:0045121],
external side of apical plasma membrane [GO:0098591],
nucleus [GO:0005634],
mitochondrion [GO:0005739],
membrane [GO:0016020],