HSPA1L

heat shock protein family A (Hsp70) member 1 like

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31965731 Primary mesenchymal stem cells derived from adipose tissue Human NO

GO terms:

Biological Process:
response to unfolded protein [GO:0006986],
binding of sperm to zona pellucida [GO:0007339],
vesicle-mediated transport [GO:0016192],
cellular response to unfolded protein [GO:0034620],
protein refolding [GO:0042026],
chaperone mediated protein folding requiring cofactor [GO:0051085],
regulation of cellular response to heat [GO:1900034],
positive regulation of protein targeting to mitochondrion [GO:1903955],
multicellular organism development [GO:0007275],
spermatogenesis [GO:0007283],
cell differentiation [GO:0030154],

Molecular Function:
protein binding [GO:0005515],
ATP binding [GO:0005524],
ATPase activity [GO:0016887],
heat shock protein binding [GO:0031072],
ubiquitin protein ligase binding [GO:0031625],
protein binding involved in protein folding [GO:0044183],
unfolded protein binding [GO:0051082],
misfolded protein binding [GO:0051787],
nucleotide binding [GO:0000166],

Cellular Component:
zona pellucida receptor complex [GO:0002199],
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
mitochondrial matrix [GO:0005759],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
COP9 signalosome [GO:0008180],
cell body [GO:0044297],
blood microparticle [GO:0072562],