ABCG1
ATP binding cassette subfamily G member 1
Link to human orthologLink to mouse ortholog
Search for interactions with genes linked to senescence.
Status in senescence: Up-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 31945125 | Primary astrocytes derived from brain | Human | YES | |
Status in senescence: Down-regulated | ||||
| Pubmed ID | Cell line | Tissue | Source | High-throughput |
| 29321003 | Primary bronchial epithelial cells derived from lung | Human | YES | |
| 33296652 | heart | heart | Human | NO |
GO terms:
Biological Process:
cholesterol metabolic process [GO:0008203],
response to organic substance [GO:0010033],
negative regulation of macrophage derived foam cell differentiation [GO:0010745],
regulation of cholesterol esterification [GO:0010872],
positive regulation of cholesterol efflux [GO:0010875],
negative regulation of cholesterol storage [GO:0010887],
intracellular cholesterol transport [GO:0032367],
cholesterol efflux [GO:0033344],
phospholipid efflux [GO:0033700],
response to lipid [GO:0033993],
lipid translocation [GO:0034204],
low-density lipoprotein particle remodeling [GO:0034374],
high-density lipoprotein particle remodeling [GO:0034375],
glycoprotein transport [GO:0034436],
cholesterol homeostasis [GO:0042632],
amyloid precursor protein catabolic process [GO:0042987],
reverse cholesterol transport [GO:0043691],
positive regulation of cholesterol biosynthetic process [GO:0045542],
positive regulation of protein secretion [GO:0050714],
transmembrane transport [GO:0055085],
phospholipid homeostasis [GO:0055091],
cellular response to high density lipoprotein particle stimulus [GO:0071403],
toxin transport [GO:1901998],
positive regulation of beta-amyloid formation [GO:1902004],
lipid transport [GO:0006869],
negative regulation of lipid storage [GO:0010888],
cholesterol transport [GO:0030301],
Molecular Function:
protein binding [GO:0005515],
ATP binding [GO:0005524],
phospholipid binding [GO:0005543],
cholesterol binding [GO:0015485],
ATPase activity [GO:0016887],
toxin transporter activity [GO:0019534],
sterol-transporting ATPase activity [GO:0034041],
protein homodimerization activity [GO:0042803],
ADP binding [GO:0043531],
protein heterodimerization activity [GO:0046982],
phosphatidylcholine-translocating ATPase activity [GO:0090554],
nucleotide binding [GO:0000166],
Cellular Component:
Golgi membrane [GO:0000139],
mitochondrion [GO:0005739],
endosome [GO:0005768],
endoplasmic reticulum membrane [GO:0005789],
Golgi apparatus [GO:0005794],
plasma membrane [GO:0005886],
external side of plasma membrane [GO:0009897],
integral component of membrane [GO:0016021],
recycling endosome [GO:0055037],
endoplasmic reticulum [GO:0005783],
membrane [GO:0016020],