anoctamin 8

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
31945125 Primary astrocytes derived from brain Human YES

GO terms:

Biological Process:
chloride transport [GO:0006821],
ion transmembrane transport [GO:0034220],
post-translational protein modification [GO:0043687],
cellular protein metabolic process [GO:0044267],
transmembrane transport [GO:0055085],
chloride transmembrane transport [GO:1902476],

Molecular Function:
intracellular calcium activated chloride channel activity [GO:0005229],
phospholipid scramblase activity [GO:0017128],

Cellular Component:
endoplasmic reticulum lumen [GO:0005788],
plasma membrane [GO:0005886],
integral component of membrane [GO:0016021],
intracellular [GO:0005622],
membrane [GO:0016020],