Search type: go_term

Results for query: enzyme binding

Gene Symbol Gene Name Links to Senescence
A2M alpha-2-macroglobulin
U: 2
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
U: 1
AKIRIN2 akirin 2
D: 1
AKT1 thymoma viral proto-oncogene 1
U: 11
D: 8
ANK1 ankyrin 1, erythroid
U: 1
ANK2 ankyrin 2
U: 1
D: 2
ANXA6 annexin A6
D: 1
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
U: 1
APOA1 apolipoprotein A-I
U: 1
APP amyloid beta (A4) precursor protein
U: 3
AR androgen receptor
U: 1
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
D: 1
ATG3 autophagy related 3
D: 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
U: 1
ATXN10 ataxin 10
U: 1
AXIN1 axin 1
D: 1
AXIN2 axin 2
U: 1
D: 1
ACSL6 acyl-CoA synthetase long-chain family member 6
U: 2
ADRB2 adrenergic receptor, beta 2
U: 1
AKAP6 A kinase (PRKA) anchor protein 6
U: 1
D: 1
ALOX5AP arachidonate 5-lipoxygenase activating protein
U: 2
D: 1
ARRB1 arrestin, beta 1
U: 1
D: 1
BACE1 beta-site APP cleaving enzyme 1
U: 2
BCL10 B cell leukemia/lymphoma 10
U: 1
D: 1
BIRC5 baculoviral IAP repeat-containing 5
U: 1
D: 8
BRCA1 breast cancer 1, early onset
U: 2
D: 7
BRD4 bromodomain containing 4
U: 1
D: 2
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
D: 1
CAPN2 calpain 2
D: 1
CASP2 caspase 2
U: 2
CAT catalase
D: 1
CAV1 caveolin 1, caveolae protein
U: 12
D: 3
CBS cystathionine beta-synthase
U: 2
D: 2
CBX1 chromobox 1
D: 1
CBX4 chromobox 4
D: 2
CCND1 cyclin D1
U: 7
D: 2
CDC20 cell division cycle 20
D: 6
CNTNAP2 contactin associated protein-like 2
U: 1
COPS5 COP9 signalosome subunit 5
D: 3
COTL1 coactosin-like 1 (Dictyostelium)
D: 1
CREB1 cAMP responsive element binding protein 1
D: 1
CSF3 colony stimulating factor 3 (granulocyte)
U: 1
D: 1
CTNNB1 catenin (cadherin associated protein), beta 1
U: 4
D: 2
CUTA cutA divalent cation tolerance homolog
U: 1
CYP1A1 cytochrome P450, family 1, subfamily a, polypeptide 1
U: 1
CYP2E1 cytochrome P450, family 2, subfamily e, polypeptide 1
U: 1
CYP3A4 cytochrome P450 family 3 subfamily A member 4
D: 1
CABYR calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)
D: 1
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
U: 1
CALU calumenin
U: 1
D: 1
CAPN3 calpain 3
U: 1
CDH2 cadherin 2
U: 1
D: 2
DAXX Fas death domain-associated protein
D: 1
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
D: 1
DFFB DNA fragmentation factor, beta subunit
D: 1
DHCR24 24-dehydrocholesterol reductase
U: 2
DIS3L DIS3 like exosome 3'-5' exoribonuclease
D: 1
DYNLL1 dynein light chain LC8-type 1
D: 1
DUOXA1 dual oxidase maturation factor 1
U: 1
ECM1 extracellular matrix protein 1
U: 3
EGFR epidermal growth factor receptor
D: 7
EGLN1 egl-9 family hypoxia-inducible factor 1
U: 1
EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3
U: 1
D: 1
EPHX1 epoxide hydrolase 1, microsomal
U: 2
ERN1 endoplasmic reticulum (ER) to nucleus signalling 1
U: 1
D: 2
ESR1 estrogen receptor 1 (alpha)
U: 1
D: 4
ESR2 estrogen receptor 2 (beta)
U: 1
D: 1
ENO1 enolase 1, alpha non-neuron
D: 1
ENO2 enolase 2, gamma neuronal
U: 3
FN1 fibronectin 1
U: 1
D: 1
FOXO4 forkhead box O4
U: 2
FYN Fyn proto-oncogene
D: 1
FXN frataxin
D: 1
GBP1 guanylate binding protein 1
U: 2
D: 1
GCH1 GTP cyclohydrolase 1
U: 1
GCKR glucokinase regulatory protein
U: 1
GCLC glutamate-cysteine ligase, catalytic subunit
D: 1
GOT2 glutamatic-oxaloacetic transaminase 2, mitochondrial
D: 1
GSTM2 glutathione S-transferase, mu 2
U: 1
GSTM4 glutathione S-transferase, mu 4
D: 1
GAPDH glyceraldehyde-3-phosphate dehydrogenase
U: 1
D: 3
GCHFR GTP cyclohydrolase I feedback regulator
U: 2
D: 1
GRIN1 glutamate receptor, ionotropic, NMDA1 (zeta 1)
U: 1
GSTM5 glutathione S-transferase, mu 5
D: 1
H2AFX H2A histone family, member X
U: 2
D: 2
H2AFY H2A histone family, member Y
U: 3
HDAC1 histone deacetylase 1
U: 2
D: 4
HDAC2 histone deacetylase 2
U: 1
D: 1
HDAC3 histone deacetylase 3
D: 1
HDAC6 histone deacetylase 6
D: 1
HIF1A hypoxia inducible factor 1, alpha subunit
U: 1
D: 8
HIST1H2AG histone cluster 1 H2A family member g
D: 1
HIST1H2AI histone cluster 1 H2A family member i
D: 1
HIST1H2AK histone cluster 1 H2A family member k
D: 1
HIST1H2AM histone cluster 1 H2A family member m
U: 1
HIST1H2BH histone cluster 1 H2B family member h
D: 1
HMGA1 high mobility group AT-hook 1
U: 1
D: 3
HMOX1 heme oxygenase 1
U: 2
D: 4
HOXA9 homeobox A9
D: 2
HSPA1A heat shock protein 1A
U: 1
D: 4
HSPA1B heat shock protein family A (Hsp70) member 1B
U: 1
D: 2
HSPA2 heat shock protein 2
U: 1
HSPA5 heat shock protein 5
U: 1
D: 3
HSPA8 heat shock protein 8
U: 1
HSPD1 heat shock protein 1 (chaperonin)
D: 1
HYAL2 hyaluronoglucosaminidase 2
U: 1
HIST1H2AC histone cluster 1, H2ac
D: 2
HMBS hydroxymethylbilane synthase
D: 2
HMGA2 high mobility group AT-hook 2
U: 1
D: 2
HSPA9 heat shock protein 9
U: 2
D: 2
IGF2R insulin-like growth factor 2 receptor
U: 1
D: 1
IL6R interleukin 6 receptor
U: 1
IQCB1 IQ calmodulin-binding motif containing 1
U: 1
ITGB3 integrin beta 3
U: 1
D: 1
ILF3 interleukin enhancer binding factor 3
D: 2
JUN jun proto-oncogene
D: 4
JUND jun D proto-oncogene
D: 1
KDM1A lysine (K)-specific demethylase 1A
D: 2
KDM4C lysine (K)-specific demethylase 4C
D: 1
KMT2E lysine (K)-specific methyltransferase 2E
U: 1
LAMP2 lysosomal-associated membrane protein 2
D: 1
LDB1 LIM domain binding 1
U: 1
LDB2 LIM domain binding 2
D: 2
LGALS9 lectin, galactose binding, soluble 9
U: 2
D: 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
D: 1
LAMB1 laminin B1
U: 1
LYN LYN proto-oncogene, Src family tyrosine kinase
D: 1
MAP2K7 mitogen-activated protein kinase kinase 7
D: 1
MAPK14 mitogen-activated protein kinase 14
U: 32
MAPK8 mitogen-activated protein kinase 8
U: 4
D: 1
MARCH6 membrane-associated ring finger (C3HC4) 6
U: 1
MAT2B methionine adenosyltransferase II, beta
D: 1
MCM10 minichromosome maintenance 10 replication initiation factor
U: 1
D: 2
MCM2 minichromosome maintenance complex component 2
D: 1
MDM2 transformed mouse 3T3 cell double minute 2
U: 3
D: 11
MDM4 transformed mouse 3T3 cell double minute 4
U: 1
D: 1
MLEC malectin
D: 1
MSN moesin
D: 2
MECP2 methyl CpG binding protein 2
U: 2
D: 3
MEF2D myocyte enhancer factor 2D
U: 1
MST1 macrophage stimulating 1 (hepatocyte growth factor-like)
U: 1
MYLK myosin, light polypeptide kinase
D: 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
U: 1
D: 2
NLRP1 NLR family pyrin domain containing 1
D: 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
D: 1
NME2 NME/NM23 nucleoside diphosphate kinase 2
D: 1
NOD2 nucleotide-binding oligomerization domain containing 2
U: 1
NOTCH1 notch 1
U: 7
D: 1
NOTCH3 notch 3
U: 4
NOXA1 NADPH oxidase activator 1
U: 2
NOXO1 NADPH oxidase organizer 1
D: 1
NR5A1 nuclear receptor subfamily 5, group A, member 1
D: 1
NPM1 nucleophosmin 1
U: 2
D: 1
NR2E1 nuclear receptor subfamily 2, group E, member 1
D: 2
OAZ1 ornithine decarboxylase antizyme 1
U: 1
P4HB prolyl 4-hydroxylase, beta polypeptide
D: 1
PARP1 poly (ADP-ribose) polymerase family, member 1
U: 3
D: 3
PARP14 poly (ADP-ribose) polymerase family, member 14
U: 3
PARP9 poly (ADP-ribose) polymerase family, member 9
U: 3
PAWR PRKC, apoptosis, WT1, regulator
U: 1
D: 1
PCBP2 poly(rC) binding protein 2
D: 1
PCNA proliferating cell nuclear antigen
U: 2
D: 2
PDE4D phosphodiesterase 4D
U: 2
PDE4DIP phosphodiesterase 4D interacting protein (myomegalin)
U: 1
D: 1
PDGFRB platelet derived growth factor receptor, beta polypeptide
D: 1
PEBP1 phosphatidylethanolamine binding protein 1
U: 2
PEX7 peroxisomal biogenesis factor 7
U: 1
PGR progesterone receptor
U: 3
D: 1
PHB prohibitin
U: 1
D: 2
PHKG1 phosphorylase kinase gamma 1
U: 1
PHKG2 phosphorylase kinase catalytic subunit gamma 2
U: 1
PIAS1 protein inhibitor of activated STAT 1
U: 1
PKP3 plakophilin 3
D: 1
PLAUR plasminogen activator, urokinase receptor
U: 2
D: 2
PLCB1 phospholipase C, beta 1
D: 1
PLCE1 phospholipase C, epsilon 1
U: 2
PLSCR4 phospholipid scramblase 4
U: 3
POLB polymerase (DNA directed), beta
D: 1
PPARA peroxisome proliferator activated receptor alpha
D: 3
PPARG peroxisome proliferator activated receptor gamma
U: 3
D: 3
PPP3CA protein phosphatase 3, catalytic subunit, alpha isoform
U: 1
PREX1 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
U: 1
PRKCA protein kinase C, alpha
U: 3
D: 1
PRKCD protein kinase C, delta
U: 5
PRKCH protein kinase C, eta
U: 2
PRKDC protein kinase, DNA activated, catalytic polypeptide
D: 1
PRKN parkin RBR E3 ubiquitin protein ligase
U: 2
PRKRA protein kinase, interferon inducible double stranded RNA dependent activator
U: 1
PRMT1 protein arginine N-methyltransferase 1
D: 3
PTEN phosphatase and tensin homolog
U: 5
D: 15
PTGS2 prostaglandin-endoperoxide synthase 2
U: 6
D: 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
U: 1
PUS7 pseudouridylate synthase 7
D: 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
D: 1
PPID peptidylprolyl isomerase D (cyclophilin D)
D: 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
U: 3
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
U: 1
D: 1
PTK2B PTK2 protein tyrosine kinase 2 beta
U: 1
RAC1 Rac family small GTPase 1
U: 4
D: 1
RACK1 receptor for activated C kinase 1
D: 1
RAD51 RAD51 recombinase
D: 4
RAD9A RAD9 checkpoint clamp component A
U: 1
RAF1 v-raf-leukemia viral oncogene 1
U: 2
RANBP9 RAN binding protein 9
D: 1
RASD2 RASD family, member 2
U: 1
RCOR2 REST corepressor 2
D: 1
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian)
U: 6
D: 1
RFC2 replication factor C (activator 1) 2
D: 1
RFC4 replication factor C (activator 1) 4
D: 2
RFC5 replication factor C (activator 1) 5
D: 2
RNF125 ring finger protein 125
U: 1
D: 1
RNF14 ring finger protein 14
D: 1
RNF144A ring finger protein 144A
U: 1
D: 2
RNF144B ring finger protein 144B
U: 3
RNF19B ring finger protein 19B
U: 1
RPAP2 RNA polymerase II associated protein 2
D: 1
RXRA retinoid X receptor alpha
U: 1
D: 1
RB1 RB transcriptional corepressor 1
U: 30
D: 2
RYR1 ryanodine receptor 1, skeletal muscle
U: 1
SAE1 SUMO1 activating enzyme subunit 1
D: 1
SCAF8 SR-related CTD-associated factor 8
D: 1
SELENOS selenoprotein S
D: 1
SIAH2 siah E3 ubiquitin protein ligase 2
D: 1
SIRT1 sirtuin 1
U: 2
D: 82
SIRT3 sirtuin 3
D: 7
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
U: 1
SORT1 sortilin 1
U: 1
SPDL1 spindle apparatus coiled-coil protein 1
D: 3
SQSTM1 sequestosome 1
U: 2
SRC Rous sarcoma oncogene
U: 1
D: 3
STAT1 signal transducer and activator of transcription 1
U: 5
D: 1
STC2 stanniocalcin 2
U: 1
D: 1
STUB1 STIP1 homology and U-Box containing protein 1
U: 2
D: 3
SUMO1 small ubiquitin-like modifier 1
U: 2
D: 1
SUMO3 small ubiquitin-like modifier 3
U: 1
SUPT5H SPT5 homolog, DSIF elongation factor subunit
D: 1
SLC18A2 solute carrier family 18 (vesicular monoamine), member 2
U: 1
SLC25A4 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
U: 2
SMAD3 SMAD family member 3
U: 5
SOD1 superoxide dismutase 1, soluble
U: 1
D: 3
SOD2 superoxide dismutase 2, mitochondrial
U: 6
D: 6
TERF2 telomeric repeat binding factor 2
U: 1
D: 4
TGFB1 transforming growth factor, beta 1
U: 30
D: 1
THRB thyroid hormone receptor beta
U: 2
D: 1
TMSB4X thymosin beta 4 X-linked
D: 2
TNKS1BP1 tankyrase 1 binding protein 1
U: 2
TOLLIP toll interacting protein
U: 1
TOP2A topoisomerase (DNA) II alpha
D: 5
TP53 tumor protein p53
U: 176
D: 8
TRAK2 trafficking protein, kinesin binding 2
U: 1
TSPAN10 tetraspanin 10
U: 2
TSPAN33 tetraspanin 33
U: 1
TSPAN5 tetraspanin 5
D: 2
TSPYL1 testis-specific protein, Y-encoded-like 1
U: 1
TSTA3 tissue specific transplantation antigen P35B
D: 1
TULP3 tubby-like protein 3
D: 1
TIMM17A translocase of inner mitochondrial membrane 17a
D: 1
TIMM44 translocase of inner mitochondrial membrane 44
D: 1
TRIB3 tribbles pseudokinase 3
U: 1
D: 2
UBE2I ubiquitin-conjugating enzyme E2I
D: 2
USP22 ubiquitin specific peptidase 22
D: 1
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
U: 1
VHL von Hippel-Lindau tumor suppressor
D: 2
VSIR V-set immunoregulatory receptor
U: 2
WDR70 WD repeat domain 70
D: 1
WWOX WW domain-containing oxidoreductase
U: 2
D: 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
U: 1
ZFHX3 zinc finger homeobox 3
U: 1
ZFP36 zinc finger protein 36
U: 2
ZNHIT6 zinc finger, HIT type 6
D: 1