Search type: go_term

Results for query: catalytic activity

Gene Symbol Gene Name Links to Senescence
AADAC arylacetamide deacetylase
D: 1
ACACB acetyl-Coenzyme A carboxylase beta
U: 3
D: 1
ALAD aminolevulinate, delta-, dehydratase
U: 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
D: 1
ALOX5AP arachidonate 5-lipoxygenase activating protein
U: 2
D: 1
ANXA2 annexin A2
U: 1
ANXA3 annexin A3
U: 2
D: 1
ANXA5 annexin A5
U: 1
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
U: 1
APOC1 apolipoprotein C1
D: 1
AR androgen receptor
U: 1
ARL2BP ADP ribosylation factor like GTPase 2 binding protein
D: 1
ATP6V1H ATPase H+ transporting V1 subunit H
U: 2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
U: 1
AUP1 AUP1 lipid droplet regulating VLDL assembly factor
U: 1
AADAT aminoadipate aminotransferase
D: 1
AASDH aminoadipate-semialdehyde dehydrogenase
D: 1
ABAT 4-aminobutyrate aminotransferase
U: 2
ABHD6 abhydrolase domain containing 6
U: 1
ABHD8 abhydrolase domain containing 8
U: 2
ACACA acetyl-Coenzyme A carboxylase alpha
D: 1
ACAT2 acetyl-Coenzyme A acetyltransferase 2
D: 1
ACLY ATP citrate lyase
U: 1
D: 1
ACSBG1 acyl-CoA synthetase bubblegum family member 1
U: 1
ACSF2 acyl-CoA synthetase family member 2
U: 2
ACSL1 acyl-CoA synthetase long-chain family member 1
U: 2
ACSL3 acyl-CoA synthetase long-chain family member 3
D: 1
ACSL5 acyl-CoA synthetase long-chain family member 5
U: 1
ACSL6 acyl-CoA synthetase long-chain family member 6
U: 2
ACSM3 acyl-CoA synthetase medium-chain family member 3
U: 1
ACSM4 acyl-CoA synthetase medium-chain family member 4
U: 1
ACSS1 acyl-CoA synthetase short-chain family member 1
U: 1
ACSS2 acyl-CoA synthetase short-chain family member 2
D: 1
ADSL adenylosuccinate lyase
D: 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
U: 3
ALAS1 aminolevulinic acid synthase 1
U: 1
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
U: 1
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
U: 1
D: 1
ALDOB aldolase B, fructose-bisphosphate
U: 1
ALDOC aldolase C, fructose-bisphosphate
U: 1
ALKBH8 alkB homolog 8, tRNA methyltransferase
D: 2
ALOXE3 arachidonate lipoxygenase 3
D: 1
ALPL alkaline phosphatase, liver/bone/kidney
U: 1
ARSA arylsulfatase A
U: 1
ARSG arylsulfatase G
U: 2
ARSI arylsulfatase i
U: 1
ARSJ arylsulfatase J
D: 1
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
U: 1
D: 1
B3GAT3 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
U: 1
BAG1 BCL2 associated athanogene 1
U: 1
BAG3 BCL2 associated athanogene 3
D: 1
BCAS3 breast carcinoma amplified sequence 3
U: 1
BCL2 B cell leukemia/lymphoma 2
U: 6
D: 2
BECN1 beclin 1, autophagy related
U: 3
D: 2
BMP2K BMP2 inducible kinase
D: 1
BCAT1 branched chain aminotransferase 1, cytosolic
U: 1
D: 1
BCAT2 branched chain aminotransferase 2, mitochondrial
U: 2
D: 1
BCKDHB branched chain ketoacid dehydrogenase E1, beta polypeptide
D: 2
BDH1 3-hydroxybutyrate dehydrogenase, type 1
U: 1
BLM Bloom syndrome, RecQ like helicase
D: 4
BPGM 2,3-bisphosphoglycerate mutase
U: 1
CAPN3 calpain 3
U: 1
CASP3 caspase 3
D: 1
CAV1 caveolin 1, caveolae protein
U: 12
D: 3
CBX8 chromobox 8
D: 1
CEL carboxyl ester lipase
U: 4
CIB1 calcium and integrin binding 1 (calmyrin)
D: 1
CLN3 ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
U: 1
CTSB cathepsin B
U: 1
CXCL1 C-X-C motif chemokine ligand 1
U: 3
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
D: 1
CAMK1 calcium/calmodulin-dependent protein kinase I
U: 1
CAST calpastatin
U: 1
D: 1
CDADC1 cytidine and dCMP deaminase domain containing 1
U: 1
CDC42 cell division cycle 42
U: 3
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
D: 1
CDYL chromodomain protein, Y chromosome-like
D: 1
CKM creatine kinase, muscle
U: 1
CLYBL citrate lyase beta like
U: 1
CPS1 carbamoyl-phosphate synthetase 1
D: 1
CRCP calcitonin gene-related peptide-receptor component protein
D: 1
CSAD cysteine sulfinic acid decarboxylase
U: 2
CTH cystathionase (cystathionine gamma-lyase)
D: 1
CYP1A1 cytochrome P450, family 1, subfamily a, polypeptide 1
U: 1
D2HGDH D-2-hydroxyglutarate dehydrogenase
U: 1
DBH dopamine beta hydroxylase
D: 1
DDAH1 dimethylarginine dimethylaminohydrolase 1
U: 1
D: 1
DIP2A disco interacting protein 2 homolog A
U: 1
DIP2C disco interacting protein 2 homolog C
D: 1
DCTD dCMP deaminase
D: 1
DCTN6 dynactin 6
U: 1
DERA deoxyribose-phosphate aldolase (putative)
D: 1
DNA2 DNA replication helicase/nuclease 2
U: 1
D: 2
DNMT1 DNA methyltransferase (cytosine-5) 1
U: 1
D: 5
DPYD dihydropyrimidine dehydrogenase
U: 1
D: 1
DUS3L dihydrouridine synthase 3-like (S. cerevisiae)
D: 1
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
D: 1
ECHDC3 enoyl Coenzyme A hydratase domain containing 3
U: 1
ESPL1 extra spindle pole bodies like 1, separase
D: 5
ECH1 enoyl coenzyme A hydratase 1, peroxisomal
U: 1
ECHDC2 enoyl Coenzyme A hydratase domain containing 2
U: 2
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
D: 1
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
U: 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
U: 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
U: 3
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
D: 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4
U: 2
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5
U: 1
EPHX1 epoxide hydrolase 1, microsomal
U: 2
EPHX4 epoxide hydrolase 4
U: 1
D: 1
EPRS glutamyl-prolyl-tRNA synthetase
D: 1
ERN1 endoplasmic reticulum (ER) to nucleus signalling 1
U: 1
D: 2
EXO1 exonuclease 1
U: 1
D: 3
FGFR4 fibroblast growth factor receptor 4
D: 1
FHIT fragile histidine triad gene
U: 1
FRY FRY microtubule binding protein
U: 1
FXN frataxin
D: 1
FAHD1 fumarylacetoacetate hydrolase domain containing 1
U: 1
FASN fatty acid synthase
U: 1
FEN1 flap structure specific endonuclease 1
D: 2
FLAD1 flavin adenine dinucleotide synthetase 1
D: 1
FNTB farnesyltransferase, CAAX box, beta
D: 1
FOLH1 folate hydrolase 1
U: 1
FTCD formiminotransferase cyclodeaminase
D: 1
FXYD3 FXYD domain-containing ion transport regulator 3
U: 1
GLA galactosidase, alpha
U: 1
D: 2
GPSM2 G protein signaling modulator 2
D: 3
GPSM3 G protein signaling modulator 3
D: 1
GRPEL1 GrpE like 1, mitochondrial
D: 1
GRPEL2 GrpE like 2, mitochondrial
D: 1
GTF3C4 general transcription factor IIIC subunit 4
D: 1
GAA glucosidase, alpha, acid
U: 2
GAD1 glutamate decarboxylase 1
U: 2
GALC galactosylceramidase
U: 2
GART phosphoribosylglycinamide formyltransferase
D: 1
GBE1 glucan (1,4-alpha-), branching enzyme 1
U: 2
GCH1 GTP cyclohydrolase 1
U: 1
GCLC glutamate-cysteine ligase, catalytic subunit
D: 1
GEN1 GEN1, Holliday junction 5' flap endonuclease
D: 1
GLUL glutamate-ammonia ligase (glutamine synthetase)
U: 1
GMPR guanosine monophosphate reductase
U: 1
GOT1 glutamic-oxaloacetic transaminase 1, soluble
D: 1
GOT2 glutamatic-oxaloacetic transaminase 2, mitochondrial
D: 1
GPHN gephyrin
U: 1
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2
D: 1
GSTZ1 glutathione transferase zeta 1 (maleylacetoacetate isomerase)
U: 1
GYS1 glycogen synthase 1, muscle
U: 1
HNRNPR heterogeneous nuclear ribonucleoprotein R
D: 2
HPGD hydroxyprostaglandin dehydrogenase 15 (NAD)
U: 2
HSD17B6 hydroxysteroid 17-beta dehydrogenase 6
U: 1
D: 1
HSPB2 heat shock protein family B (small) member 2
D: 1
HSPBP1 HSPA (Hsp70) binding protein 1
D: 2
HADHA hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
U: 2
HADHB hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
U: 2
HIF1A hypoxia inducible factor 1, alpha subunit
U: 1
D: 8
HK2 hexokinase 2
U: 1
D: 1
HMGCL 3-hydroxy-3-methylglutaryl-Coenzyme A lyase
U: 1
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
U: 2
HSPA8 heat shock protein 8
U: 1
HYAL1 hyaluronoglucosaminidase 1
U: 1
HYAL2 hyaluronoglucosaminidase 2
U: 1
HYAL4 hyaluronoglucosaminidase 4
D: 1
IGF2 insulin-like growth factor 2
U: 1
ISOC1 isochorismatase domain containing 1
D: 1
ITPK1 inositol-tetrakisphosphate 1-kinase
U: 1
IDS iduronate 2-sulfatase
U: 1
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 2C
D: 1
IMPDH2 inosine monophosphate dehydrogenase 2
D: 1
KLHL3 kelch-like 3
U: 3
KYAT1 kynurenine aminotransferase 1
U: 1
D: 1
KYNU kynureninase
D: 1
LGI3 leucine-rich repeat LGI family, member 3
U: 2
LTC4S leukotriene C4 synthase
U: 1
LANCL1 LanC (bacterial lantibiotic synthetase component C)-like 1
U: 1
LARGE1 LARGE xylosyl- and glucuronyltransferase 1
U: 1
LDHA lactate dehydrogenase A
U: 1
D: 1
LEP leptin
U: 1
LGSN lengsin, lens protein with glutamine synthetase domain
D: 1
LIAS lipoic acid synthetase
D: 1
MAT2B methionine adenosyltransferase 2B
D: 1
MED16 mediator complex subunit 16
D: 1
MMP15 matrix metallopeptidase 15
U: 1
MMP24 matrix metallopeptidase 24
U: 2
MT3 metallothionein 3
U: 1
MAN1A2 mannosidase, alpha, class 1A, member 2
D: 1
MAN1B1 mannosidase, alpha, class 1B, member 1
U: 1
MAN2A1 mannosidase 2, alpha 1
U: 1
MAN2A2 mannosidase 2, alpha 2
U: 2
MDH1 malate dehydrogenase 1, NAD (soluble)
D: 1
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
U: 1
D: 2
MEST mesoderm specific transcript
U: 1
MOCOS molybdenum cofactor sulfurase
D: 1
MOCS1 molybdenum cofactor synthesis 1
U: 1
MOXD1 monooxygenase, DBH-like 1
U: 1
D: 1
MTAP methylthioadenosine phosphorylase
D: 1
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
D: 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
U: 1
D: 1
MTHFR methylenetetrahydrofolate reductase
U: 1
D: 1
MUTYH mutY DNA glycosylase
D: 1
MYC myelocytomatosis oncogene
U: 4
D: 19
NCF2 neutrophil cytosolic factor 2
U: 2
NCF4 neutrophil cytosolic factor 4
U: 1
NES nestin
D: 2
NOTCH1 notch 1
U: 7
D: 1
NOXA1 NADPH oxidase activator 1
U: 2
NOXO1 NADPH oxidase organizer 1
D: 1
NQO1 NAD(P)H dehydrogenase, quinone 1
U: 1
D: 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
D: 1
NSMAF neutral sphingomyelinase activation associated factor
U: 1
D: 1
NUPR1 nuclear protein 1, transcriptional regulator
U: 3
D: 2
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
U: 1
D: 1
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1
D: 1
NAMPT nicotinamide phosphoribosyltransferase
U: 1
D: 4
NANS N-acetylneuraminic acid synthase (sialic acid synthase)
D: 1
NAPRT nicotinate phosphoribosyltransferase
D: 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
U: 1
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
U: 1
NEIL1 nei endonuclease VIII-like 1 (E. coli)
U: 1
NEIL2 nei like 2 (E. coli)
U: 1
D: 1
NEIL3 nei like 3 (E. coli)
D: 4
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
U: 3
D: 1
NMNAT3 nicotinamide nucleotide adenylyltransferase 3
U: 1
NPM1 nucleophosmin 1
U: 2
D: 1
NTHL1 nth (endonuclease III)-like 1 (E.coli)
D: 1
OAZ1 ornithine decarboxylase antizyme 1
U: 1
OAZ2 ornithine decarboxylase antizyme 2
U: 1
OAZ3 ornithine decarboxylase antizyme 3
U: 1
OAT ornithine aminotransferase
U: 1
ODC1 ornithine decarboxylase, structural 1
U: 1
D: 1
OGG1 8-oxoguanine DNA-glycosylase 1
D: 6
OGT O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
U: 1
D: 1
OPLAH 5-oxoprolinase (ATP-hydrolysing)
U: 1
PARP1 poly (ADP-ribose) polymerase family, member 1
U: 3
D: 3
PARP3 poly(ADP-ribose) polymerase family member 3
U: 1
PARP9 poly (ADP-ribose) polymerase family, member 9
U: 3
PINLYP phospholipase A2 inhibitor and LY6/PLAUR domain containing
U: 1
PPP1R12B protein phosphatase 1 regulatory subunit 12B
U: 1
D: 1
PPP1R12C protein phosphatase 1 regulatory subunit 12C
U: 1
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
U: 1
D: 1
PRKRA protein activator of interferon induced protein kinase EIF2AK2
U: 1
PRNP prion protein
U: 2
D: 1
PSEN1 presenilin 1
U: 2
PSEN2 presenilin 2
U: 1
PSENEN presenilin enhancer gamma secretase subunit
D: 1
PSMD2 proteasome 26S subunit, non-ATPase 2
U: 1
D: 1
PSMD3 proteasome 26S subunit, non-ATPase 3
D: 2
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
D: 1
PAK1 p21 (RAC1) activated kinase 1
D: 1
PAM peptidylglycine alpha-amidating monooxygenase
U: 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
D: 1
PCYT1A phosphate cytidylyltransferase 1, choline, alpha isoform
U: 1
PDE10A phosphodiesterase 10A
D: 1
PDE11A phosphodiesterase 11A
U: 1
PDE5A phosphodiesterase 5A, cGMP-specific
D: 1
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
U: 1
PFKM phosphofructokinase, muscle
U: 1
PGAM2 phosphoglycerate mutase 2
U: 2
PGGHG protein glucosylgalactosylhydroxylysine glucosidase
U: 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
D: 1
PKIA protein kinase inhibitor, alpha
D: 1
PLD1 phospholipase D1
U: 2
D: 1
PLD2 phospholipase D2
D: 1
PLD3 phospholipase D family, member 3
U: 2
PLD6 phospholipase D family, member 6
U: 1
PPCDC phosphopantothenoylcysteine decarboxylase
U: 1
D: 1
PPM1B protein phosphatase 1B, magnesium dependent, beta isoform
D: 1
PPM1D protein phosphatase 1D magnesium-dependent, delta isoform
U: 1
D: 5
PPM1E protein phosphatase 1E (PP2C domain containing)
U: 1
PPM1H protein phosphatase 1H (PP2C domain containing)
U: 1
PPM1L protein phosphatase 1 (formerly 2C)-like
U: 1
PPM1M protein phosphatase 1M
U: 1
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
U: 1
PPTC7 PTC7 protein phosphatase homolog
U: 1
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
D: 1
PRKG1 protein kinase, cGMP-dependent, type I
U: 1
PSAT1 phosphoserine aminotransferase 1
U: 1
D: 1
PYGL liver glycogen phosphorylase
U: 1
QPRT quinolinate phosphoribosyltransferase
D: 1
RALGDS ral guanine nucleotide dissociation stimulator
U: 2
RIMS1 regulating synaptic membrane exocytosis 1
U: 1
RPE ribulose-5-phosphate-3-epimerase
D: 1
RRM1 ribonucleotide reductase M1
D: 1
RTCA RNA 3'-terminal phosphate cyclase
U: 1
D: 1
SAE1 SUMO1 activating enzyme subunit 1
D: 1
SCG5 secretogranin V
D: 1
SCGB1A1 secretoglobin family 1A member 1
D: 1
SERPINB3 serpin family B member 3
U: 1
SGK1 serum/glucocorticoid regulated kinase 1
U: 1
D: 3
SH3BP4 SH3-domain binding protein 4
D: 1
SH3PXD2A SH3 and PX domains 2A
U: 2
SIL1 SIL1 nucleotide exchange factor
U: 1
SIRPA signal regulatory protein alpha
U: 2
SLC3A2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
U: 1
D: 1
SLN sarcolipin
U: 1
SOD1 superoxide dismutase 1, soluble
U: 1
D: 3
SPATA20 spermatogenesis associated 20
U: 1
D: 1
SREBF1 sterol regulatory element binding transcription factor 1
U: 3
STX4 syntaxin 4
U: 2
SAMHD1 SAM domain and HD domain, 1
U: 1
SCLY selenocysteine lyase
D: 3
SGPL1 sphingosine phosphate lyase 1
D: 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
U: 2
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
D: 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
U: 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
U: 2
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
U: 1
D: 1
SOD2 superoxide dismutase 2, mitochondrial
U: 6
D: 6
SPAM1 sperm adhesion molecule 1
U: 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
D: 1
SRM spermidine synthase
D: 2
SRR serine racemase
D: 1
ST6GAL2 beta galactoside alpha 2,6 sialyltransferase 2
U: 1
STS steroid sulfatase
U: 1
SUCLG2 succinate-Coenzyme A ligase, GDP-forming, beta subunit
D: 1
SUGCT succinyl-CoA glutarate-CoA transferase
U: 1
SULF1 sulfatase 1
U: 1
SULF2 sulfatase 2
U: 2
TGM3 transglutaminase 3, E polypeptide
U: 2
TIMP1 tissue inhibitor of metalloproteinase 1
U: 1
D: 1
TPD52L2 TPD52 like 2
D: 1
TREX1 three prime repair exonuclease 1
U: 1
D: 1
TRIM23 tripartite motif containing 23
U: 1
TXNIP thioredoxin interacting protein
U: 5
D: 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
D: 1
TAT tyrosine aminotransferase
U: 1
TIGAR Trp53 induced glycolysis repulatory phosphatase
U: 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
U: 1
TSTA3 tissue specific transplantation antigen P35B
D: 1
UEVLD UEV and lactate/malate dehyrogenase domains
D: 1
UGDH UDP-glucose dehydrogenase
D: 1
UPP1 uridine phosphorylase 1
U: 2
D: 1
WDTC1 WD and tetratricopeptide repeats 1
U: 1
WRN Werner syndrome RecQ like helicase
D: 8
XRCC5 X-ray repair cross complementing 5
D: 4
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
D: 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
U: 1
YDJC YdjC homolog (bacterial)
D: 1
ZRANB3 zinc finger, RAN-binding domain containing 3
D: 1