BCL2L11

BCL2 like 11

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
in utero embryonic development [GO:0001701],
B cell homeostasis [GO:0001782],
B cell apoptotic process [GO:0001783],
kidney development [GO:0001822],
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:0001844],
myeloid cell homeostasis [GO:0002262],
apoptotic process [GO:0006915],
cell-matrix adhesion [GO:0007160],
spermatogenesis [GO:0007283],
brain development [GO:0007420],
male gonad development [GO:0008584],
intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630],
mammary gland development [GO:0030879],
positive regulation of protein homooligomerization [GO:0032464],
autophagy in response to ER overload [GO:0034263],
response to endoplasmic reticulum stress [GO:0034976],
tube formation [GO:0035148],
odontogenesis of dentin-containing tooth [GO:0042475],
regulation of apoptotic process [GO:0042981],
T cell homeostasis [GO:0043029],
positive regulation of apoptotic process [GO:0043065],
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043280],
positive regulation of neuron apoptotic process [GO:0043525],
ear development [GO:0043583],
positive regulation of cell cycle [GO:0045787],
regulation of organ growth [GO:0046620],
developmental pigmentation [GO:0048066],
regulation of developmental pigmentation [GO:0048070],
spleen development [GO:0048536],
thymus development [GO:0048538],
post-embryonic animal organ morphogenesis [GO:0048563],
positive regulation of apoptotic process by virus [GO:0060139],
cellular process regulating host cell cycle in response to virus [GO:0060154],
thymocyte apoptotic process [GO:0070242],
cellular response to glucocorticoid stimulus [GO:0071385],
positive regulation of release of cytochrome c from mitochondria [GO:0090200],
extrinsic apoptotic signaling pathway in absence of ligand [GO:0097192],
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway [GO:1902237],
apoptotic process involved in embryonic digit morphogenesis [GO:1902263],
positive regulation of IRE1-mediated unfolded protein response [GO:1903896],
positive regulation of fibroblast apoptotic process [GO:2000271],
positive regulation of intrinsic apoptotic signaling pathway [GO:2001244],
leukocyte homeostasis [GO:0001776],
lymphocyte homeostasis [GO:0002260],
activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919],
post-embryonic development [GO:0009791],
positive regulation of cell death [GO:0010942],
positive regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902110],

Molecular Function:
protein binding [GO:0005515],
microtubule binding [GO:0008017],
protein kinase binding [GO:0019901],
protein heterodimerization activity [GO:0046982],
dynein complex binding [GO:0070840],

Cellular Component:
mitochondrion [GO:0005739],
mitochondrial outer membrane [GO:0005741],
cytosol [GO:0005829],
endomembrane system [GO:0012505],
extrinsic component of membrane [GO:0019898],
Bcl-2 family protein complex [GO:0097136],
cytoplasm [GO:0005737],
microtubule [GO:0005874],
membrane [GO:0016020],
intracellular membrane-bounded organelle [GO:0043231],
BIM-BCL-xl complex [GO:0097140],
BIM-BCL-2 complex [GO:0097141],