BCL11B

BAF chromatin remodeling complex subunit BCL11B

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

GO terms:

Biological Process:
keratinocyte development [GO:0003334],
epithelial cell morphogenesis [GO:0003382],
regulation of transcription, DNA-templated [GO:0006355],
axonogenesis [GO:0007409],
negative regulation of cell proliferation [GO:0008285],
post-embryonic development [GO:0009791],
regulation of gene expression [GO:0010468],
regulation of keratinocyte proliferation [GO:0010837],
regulation of lipid metabolic process [GO:0019216],
striatal medium spiny neuron differentiation [GO:0021773],
commitment of neuronal cell to specific neuron type in forebrain [GO:0021902],
central nervous system neuron differentiation [GO:0021953],
post-embryonic camera-type eye development [GO:0031077],
T cell differentiation in thymus [GO:0033077],
T cell receptor V(D)J recombination [GO:0033153],
hematopoietic stem cell migration [GO:0035701],
odontogenesis of dentin-containing tooth [GO:0042475],
negative regulation of apoptotic process [GO:0043066],
positive T cell selection [GO:0043368],
skin development [GO:0043588],
regulation of neuron differentiation [GO:0045664],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
alpha-beta T cell differentiation [GO:0046632],
thymus development [GO:0048538],
olfactory bulb axon guidance [GO:0071678],
lymphoid lineage cell migration into thymus [GO:0097535],

Molecular Function:
RNA polymerase II core promoter proximal region sequence-specific DNA binding [GO:0000978],
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding [GO:0001228],
nucleic acid binding [GO:0003676],
transcription factor activity, sequence-specific DNA binding [GO:0003700],
protein binding [GO:0005515],
sequence-specific DNA binding [GO:0043565],
metal ion binding [GO:0046872],
RNA polymerase II transcription factor activity, sequence-specific DNA binding [GO:0000981],

Cellular Component:
nucleus [GO:0005634],
neuron projection [GO:0043005],