ACAT2

acetyl-CoA acetyltransferase 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
lipid metabolic process [GO:0006629],
fatty acid beta-oxidation [GO:0006635],
cholesterol biosynthetic process [GO:0006695],
positive regulation of intestinal cholesterol absorption [GO:0045797],

Molecular Function:
acetyl-CoA C-acetyltransferase activity [GO:0003985],
acetyl-CoA C-acyltransferase activity [GO:0003988],
protein binding [GO:0005515],
catalytic activity [GO:0003824],
transferase activity [GO:0016740],
transferase activity, transferring acyl groups [GO:0016746],
transferase activity, transferring acyl groups other than amino-acyl groups [GO:0016747],

Cellular Component:
nucleus [GO:0005634],
nucleolus [GO:0005730],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],
cytosol [GO:0005829],
extracellular exosome [GO:0070062],