BCAS3 microtubule associated cell migration factor

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
angiogenesis [GO:0001525],
Golgi organization [GO:0007030],
positive regulation of endothelial cell migration [GO:0010595],
microtubule organizing center organization [GO:0031023],
negative regulation of GTPase activity [GO:0034260],
tube formation [GO:0035148],
response to starvation [GO:0042594],
positive regulation of catalytic activity [GO:0043085],
positive regulation of GTPase activity [GO:0043547],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
positive regulation of filopodium assembly [GO:0051491],
negative regulation of focal adhesion assembly [GO:0051895],
cellular response to estrogen stimulus [GO:0071391],
positive regulation of intracellular protein transport [GO:0090316],
activation of GTPase activity [GO:0090630],
regulation of establishment of cell polarity [GO:2000114],
positive regulation of actin cytoskeleton reorganization [GO:2000251],

Molecular Function:
chromatin binding [GO:0003682],
protein binding [GO:0005515],
transcription factor binding [GO:0008134],
acetyltransferase activator activity [GO:0010698],
histone acetyltransferase binding [GO:0035035],
nuclear hormone receptor binding [GO:0035257],
histone binding [GO:0042393],
beta-tubulin binding [GO:0048487],

Cellular Component:
nucleus [GO:0005634],
nucleolus [GO:0005730],
cytoplasm [GO:0005737],
cytoplasmic microtubule [GO:0005881],
cell leading edge [GO:0031252],
transcriptionally active chromatin [GO:0035327],
intermediate filament cytoskeleton [GO:0045111],
cell periphery [GO:0071944],
cytoskeleton [GO:0005856],