BBOX1

gamma-butyrobetaine hydroxylase 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2 Human YES

GO terms:

Biological Process:
carnitine biosynthetic process [GO:0045329],
oxidation-reduction process [GO:0055114],

Molecular Function:
iron ion binding [GO:0005506],
protein binding [GO:0005515],
zinc ion binding [GO:0008270],
gamma-butyrobetaine dioxygenase activity [GO:0008336],
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [GO:0016702],
identical protein binding [GO:0042802],
oxidoreductase activity [GO:0016491],
metal ion binding [GO:0046872],
dioxygenase activity [GO:0051213],

Cellular Component:
mitochondrion [GO:0005739],
cytosol [GO:0005829],
extracellular exosome [GO:0070062],
cytoplasm [GO:0005737],