ACAD8

acyl-CoA dehydrogenase family member 8

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA641 Skin, Lung Human YES

GO terms:

Biological Process:
valine catabolic process [GO:0006574],
lipid metabolic process [GO:0006629],
branched-chain amino acid catabolic process [GO:0009083],
oxidation-reduction process [GO:0055114],

Molecular Function:
acyl-CoA dehydrogenase activity [GO:0003995],
flavin adenine dinucleotide binding [GO:0050660],
oxidoreductase activity [GO:0016491],
oxidoreductase activity, acting on the CH-CH group of donors [GO:0016627],

Cellular Component:
mitochondrial matrix [GO:0005759],
mitochondrion [GO:0005739],