ATPase H+ transporting V1 subunit H

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA57 Skin, Lung Human YES
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
endocytosis [GO:0006897],
vacuolar acidification [GO:0007035],
insulin receptor signaling pathway [GO:0008286],
ATP hydrolysis coupled proton transport [GO:0015991],
regulation of macroautophagy [GO:0016241],
transferrin transport [GO:0033572],
ion transmembrane transport [GO:0034220],
regulation of defense response to virus by virus [GO:0050690],
regulation of catalytic activity [GO:0050790],
phagosome acidification [GO:0090383],
ion transport [GO:0006811],

Molecular Function:
protein binding [GO:0005515],
ATPase activity [GO:0016887],
enzyme regulator activity [GO:0030234],
proton-transporting ATPase activity, rotational mechanism [GO:0046961],

Cellular Component:
vacuolar proton-transporting V-type ATPase, V1 domain [GO:0000221],
lysosomal membrane [GO:0005765],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
extracellular exosome [GO:0070062],