ATP6V1E1

ATPase H+ transporting V1 subunit E1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES

GO terms:

Biological Process:
insulin receptor signaling pathway [GO:0008286],
ATP hydrolysis coupled proton transport [GO:0015991],
regulation of macroautophagy [GO:0016241],
transferrin transport [GO:0033572],
ion transmembrane transport [GO:0034220],
phagosome acidification [GO:0090383],
hydrogen ion transmembrane transport [GO:1902600],
ion transport [GO:0006811],

Molecular Function:
protein binding [GO:0005515],
hydrogen-exporting ATPase activity, phosphorylative mechanism [GO:0008553],
proton-transporting ATPase activity, rotational mechanism [GO:0046961],
ATPase binding [GO:0051117],
hydrolase activity [GO:0016787],

Cellular Component:
lysosomal membrane [GO:0005765],
endosome [GO:0005768],
cytosol [GO:0005829],
microvillus [GO:0005902],
apical plasma membrane [GO:0016324],
proton-transporting two-sector ATPase complex [GO:0016469],
proton-transporting two-sector ATPase complex, catalytic domain [GO:0033178],
extracellular exosome [GO:0070062],
cytoplasm [GO:0005737],
mitochondrion [GO:0005739],