ATP2B1

ATPase plasma membrane Ca2+ transporting 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
negative regulation of cytokine production [GO:0001818],
regulation of vascular smooth muscle contraction [GO:0003056],
neural retina development [GO:0003407],
cellular calcium ion homeostasis [GO:0006874],
brain development [GO:0007420],
aging [GO:0007568],
regulation of blood pressure [GO:0008217],
response to cold [GO:0009409],
positive regulation of bone mineralization [GO:0030501],
ion transmembrane transport [GO:0034220],
regulation of cytosolic calcium ion concentration [GO:0051480],
negative regulation of cytosolic calcium ion concentration [GO:0051481],
positive regulation of calcium ion transport [GO:0051928],
calcium ion transmembrane transport [GO:0070588],
cellular response to vitamin D [GO:0071305],
cellular response to corticosterone stimulus [GO:0071386],
regulation of presynaptic cytosolic calcium ion concentration [GO:0099509],
regulation of cellular response to insulin stimulus [GO:1900076],
regulation of cardiac conduction [GO:1903779],
calcium ion export from cell [GO:1990034],
ion transport [GO:0006811],
calcium ion transport [GO:0006816],
calcium ion export [GO:1901660],

Molecular Function:
calcium-transporting ATPase activity [GO:0005388],
protein binding [GO:0005515],
calmodulin binding [GO:0005516],
ATP binding [GO:0005524],
calcium ion transmembrane transporter activity [GO:0015085],
ATPase activity [GO:0016887],
PDZ domain binding [GO:0030165],
metal ion binding [GO:0046872],
calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration [GO:1905056],
nucleotide binding [GO:0000166],

Cellular Component:
immunological synapse [GO:0001772],
nucleus [GO:0005634],
plasma membrane [GO:0005886],
integral component of plasma membrane [GO:0005887],
cytoplasmic side of plasma membrane [GO:0009898],
membrane [GO:0016020],
basolateral plasma membrane [GO:0016323],
apical plasma membrane [GO:0016324],
dendritic spine membrane [GO:0032591],
neuronal cell body membrane [GO:0032809],
membrane raft [GO:0045121],
extracellular exosome [GO:0070062],
glutamatergic synapse [GO:0098978],
GABA-ergic synapse [GO:0098982],
integral component of presynaptic active zone membrane [GO:0099059],
integral component of membrane [GO:0016021],
cell junction [GO:0030054],
dendrite membrane [GO:0032590],
apical part of cell [GO:0045177],
synapse [GO:0045202],