ATAD2

ATPase family AAA domain containing 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
23691139 Huh7, Hnheps, HepG2, Hep3B, Hep4, PLC/PRF/5, SNU-387, SNU- 398, SNU-423, SNU-449, SNU-475, FOCUS, Mahlavu, SK- Hep-1, FLC4 Liver Human NO
30987592 MCF7 Breast Human YES

GO terms:

Biological Process:
chromatin organization [GO:0006325],
regulation of transcription from RNA polymerase II promoter [GO:0006357],
negative regulation of chromatin silencing [GO:0031936],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
regulation of transcription, DNA-templated [GO:0006355],

Molecular Function:
chromatin binding [GO:0003682],
protein binding [GO:0005515],
ATP binding [GO:0005524],
ATPase activity [GO:0016887],
histone binding [GO:0042393],
nucleotide binding [GO:0000166],
hydrolase activity [GO:0016787],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
extracellular exosome [GO:0070062],