ASCC1

activating signal cointegrator 1 complex subunit 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA65 Skin, Lung Human YES

GO terms:

Biological Process:
DNA dealkylation involved in DNA repair [GO:0006307],
regulation of transcription, DNA-templated [GO:0006355],
DNA repair [GO:0006281],
cellular response to DNA damage stimulus [GO:0006974],

Molecular Function:
RNA binding [GO:0003723],
protein binding [GO:0005515],
nucleic acid binding [GO:0003676],
transcription coactivator activity [GO:0003713],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
transcription factor complex [GO:0005667],
nuclear speck [GO:0016607],
neuromuscular junction [GO:0031594],