ARPC1B

actin related protein 2/3 complex subunit 1B

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
21628992 Saos-2 Human NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
response to estradiol [GO:0032355],
Arp2/3 complex-mediated actin nucleation [GO:0034314],
Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096],
response to estrogen [GO:0043627],
ephrin receptor signaling pathway [GO:0048013],
regulation of actin filament polymerization [GO:0030833],

Molecular Function:
structural constituent of cytoskeleton [GO:0005200],
protein binding [GO:0005515],
actin filament binding [GO:0051015],
actin binding [GO:0003779],
macromolecular complex binding [GO:0044877],

Cellular Component:
nucleus [GO:0005634],
cytosol [GO:0005829],
Arp2/3 protein complex [GO:0005885],
focal adhesion [GO:0005925],
actin cytoskeleton [GO:0015629],
tubulobulbar complex [GO:0036284],
extracellular exosome [GO:0070062],
cytoplasm [GO:0005737],
cytoskeleton [GO:0005856],