AT-rich interaction domain 1B

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
23660946 SW199, CFPAC-1, PANC 1.5, PANC 8.13, HPDE, HPAF-II Pancreas Human NO
27737960 MEF, IMR-90 Liver Mouse NO

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF, HCA428 Skin, Lung Human YES

GO terms:

Biological Process:
chromatin remodeling [GO:0006338],
regulation of transcription from RNA polymerase II promoter [GO:0006357],
nervous system development [GO:0007399],
chromatin-mediated maintenance of transcription [GO:0048096],
chromatin organization [GO:0006325],
neuron-neuron synaptic transmission [GO:0007270],
dendritic spine development [GO:0060996],
dendritic cell dendrite assembly [GO:0097026],

Molecular Function:
RNA polymerase II transcription factor activity, sequence-specific DNA binding [GO:0000981],
DNA binding [GO:0003677],
transcription coactivator activity [GO:0003713],
protein binding [GO:0005515],

Cellular Component:
nucleoplasm [GO:0005654],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
SWI/SNF complex [GO:0016514],
nBAF complex [GO:0071565],
nucleus [GO:0005634],
cytoplasm [GO:0005737],