ARHGEF39

Rho guanine nucleotide exchange factor 39

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES
30987592 MCF7 Breast Human YES

GO terms:

Biological Process:
positive regulation of cell migration [GO:0030335],
regulation of Rho protein signal transduction [GO:0035023],

Molecular Function:
Rho guanyl-nucleotide exchange factor activity [GO:0005089],
protein binding [GO:0005515],
molecular_function [GO:0003674],
guanyl-nucleotide exchange factor activity [GO:0005085],

Cellular Component:
plasma membrane [GO:0005886],
membrane [GO:0016020],