Rho GTPase activating protein 31

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Li Fraumeni Human YES

GO terms:

Biological Process:
signal transduction [GO:0007165],
small GTPase mediated signal transduction [GO:0007264],
positive regulation of GTPase activity [GO:0043547],
regulation of small GTPase mediated signal transduction [GO:0051056],

Molecular Function:
GTPase activator activity [GO:0005096],
protein binding [GO:0005515],
SH3 domain binding [GO:0017124],

Cellular Component:
lamellipodium [GO:0030027],
cell junction [GO:0030054],
cell projection [GO:0042995],
cytosol [GO:0005829],
focal adhesion [GO:0005925],