ARHGAP18

Rho GTPase activating protein 18

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
20664062 HUVEC Artery Human, mouse NO

GO terms:

Biological Process:
signal transduction [GO:0007165],
small GTPase mediated signal transduction [GO:0007264],
regulation of cell shape [GO:0008360],
regulation of actin filament polymerization [GO:0030833],
regulation of actin cytoskeleton organization [GO:0032956],
regulation of small GTPase mediated signal transduction [GO:0051056],
regulation of cell motility [GO:2000145],
positive regulation of GTPase activity [GO:0043547],

Molecular Function:
GTPase activator activity [GO:0005096],
cadherin binding [GO:0045296],

Cellular Component:
cytoplasm [GO:0005737],
cytosol [GO:0005829],
plasma membrane [GO:0005886],
nuclear speck [GO:0016607],