ABCG2

ATP binding cassette subfamily G member 2 (Junior blood group)

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

GO terms:

Biological Process:
drug transmembrane transport [GO:0006855],
cellular iron ion homeostasis [GO:0006879],
response to drug [GO:0042493],
xenobiotic transport [GO:0042908],
urate metabolic process [GO:0046415],
transmembrane transport [GO:0055085],
urate transport [GO:0015747],
drug transport [GO:0015893],
glucuronoside metabolic process [GO:0019389],
drug export [GO:0046618],
embryonic process involved in female pregnancy [GO:0060136],
negative regulation of intestinal absorption [GO:1904479],

Molecular Function:
transporter activity [GO:0005215],
protein binding [GO:0005515],
ATP binding [GO:0005524],
xenobiotic-transporting ATPase activity [GO:0008559],
ATPase activity, coupled to transmembrane movement of substances [GO:0042626],
identical protein binding [GO:0042802],
protein homodimerization activity [GO:0042803],
nucleotide binding [GO:0000166],
cytoskeletal protein binding [GO:0008092],
drug transmembrane transporter activity [GO:0015238],
ATPase activity [GO:0016887],
protein dimerization activity [GO:0046983],

Cellular Component:
nucleus [GO:0005634],
plasma membrane [GO:0005886],
integral component of membrane [GO:0016021],
mitochondrial membrane [GO:0031966],
mitochondrion [GO:0005739],
membrane [GO:0016020],
apical plasma membrane [GO:0016324],