APOL1

apolipoprotein L1

Link to human ortholog


Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
12837283 NHOK Human NO
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2 Human YES

GO terms:

Biological Process:
lipid transport [GO:0006869],
receptor-mediated endocytosis [GO:0006898],
cholesterol metabolic process [GO:0008203],
cytolysis [GO:0019835],
killing of cells of other organism [GO:0031640],
lipoprotein metabolic process [GO:0042157],
post-translational protein modification [GO:0043687],
cellular protein metabolic process [GO:0044267],
innate immune response [GO:0045087],
chloride transmembrane transport [GO:1902476],

Molecular Function:
chloride channel activity [GO:0005254],
protein binding [GO:0005515],
lipid binding [GO:0008289],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
endoplasmic reticulum lumen [GO:0005788],
intrinsic component of membrane [GO:0031224],
very-low-density lipoprotein particle [GO:0034361],
high-density lipoprotein particle [GO:0034364],
blood microparticle [GO:0072562],