APLP1

amyloid beta precursor like protein 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
27323328 Saos-2,H1299, HT18, MCF7, MDA-MB-231, Li-Fraumeni Human YES
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES
29321003 Primary bronchial epithelial cells derived from lung Human YES
29548335 Saos-2, Li-Fraumeni Human YES

GO terms:

Biological Process:
endocytosis [GO:0006897],
apoptotic process [GO:0006915],
cell adhesion [GO:0007155],
nervous system development [GO:0007399],
animal organ morphogenesis [GO:0009887],
cellular response to norepinephrine stimulus [GO:0071874],
mRNA polyadenylation [GO:0006378],
regulation of translation [GO:0006417],
extracellular matrix organization [GO:0030198],
forebrain development [GO:0030900],

Molecular Function:
protein binding [GO:0005515],
heparin binding [GO:0008201],
alpha-2A adrenergic receptor binding [GO:0031694],
alpha-2B adrenergic receptor binding [GO:0031695],
alpha-2C adrenergic receptor binding [GO:0031696],
identical protein binding [GO:0042802],
transition metal ion binding [GO:0046914],
metal ion binding [GO:0046872],

Cellular Component:
basement membrane [GO:0005604],
plasma membrane [GO:0005886],
integral component of membrane [GO:0016021],
perinuclear region of cytoplasm [GO:0048471],
cytoplasm [GO:0005737],
Golgi apparatus [GO:0005794],
membrane [GO:0016020],