APBB1

amyloid beta precursor protein binding family B member 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29321003 Primary bronchial epithelial cells derived from lung Human YES

GO terms:

Biological Process:
negative regulation of transcription from RNA polymerase II promoter [GO:0000122],
double-strand break repair [GO:0006302],
regulation of transcription, DNA-templated [GO:0006355],
apoptotic process [GO:0006915],
cellular response to DNA damage stimulus [GO:0006974],
cell cycle arrest [GO:0007050],
signal transduction [GO:0007165],
axonogenesis [GO:0007409],
response to iron ion [GO:0010039],
positive regulation of neuron projection development [GO:0010976],
negative regulation of cell growth [GO:0030308],
positive regulation of apoptotic process [GO:0043065],
histone H4 acetylation [GO:0043967],
positive regulation of DNA repair [GO:0045739],
positive regulation of transcription, DNA-templated [GO:0045893],
positive regulation of transcription from RNA polymerase II promoter [GO:0045944],
positive regulation of protein secretion [GO:0050714],
negative regulation of thymidylate synthase biosynthetic process [GO:0050760],
neuron migration [GO:0001764],
chromatin organization [GO:0006325],
axon guidance [GO:0007411],
visual learning [GO:0008542],
actin filament-based movement [GO:0030048],
extracellular matrix organization [GO:0030198],
negative regulation of neuron differentiation [GO:0045665],
synapse organization [GO:0050808],
protein stabilization [GO:0050821],

Molecular Function:
beta-amyloid binding [GO:0001540],
chromatin binding [GO:0003682],
protein binding [GO:0005515],
transcription factor binding [GO:0008134],
ubiquitin protein ligase binding [GO:0031625],
histone binding [GO:0042393],
macromolecular complex binding [GO:0044877],
tau protein binding [GO:0048156],
proline-rich region binding [GO:0070064],
histone acetyltransferase binding [GO:0035035],

Cellular Component:
nucleus [GO:0005634],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
plasma membrane [GO:0005886],
nuclear speck [GO:0016607],
lamellipodium [GO:0030027],
growth cone [GO:0030426],
macromolecular complex [GO:0032991],
presynaptic membrane [GO:0042734],
neuronal cell body [GO:0043025],
dendritic spine [GO:0043197],
main axon [GO:0044304],
synapse [GO:0045202],
postsynaptic membrane [GO:0045211],
perinuclear region of cytoplasm [GO:0048471],
growth cone lamellipodium [GO:1990761],
growth cone filopodium [GO:1990812],
membrane [GO:0016020],
neuromuscular junction [GO:0031594],
cell projection [GO:0042995],
presynapse [GO:0098793],
glutamatergic synapse [GO:0098978],