IL15

interleukin 15

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2 Human YES

GO terms:

Biological Process:
natural killer cell differentiation [GO:0001779],
NK T cell proliferation [GO:0001866],
inflammatory response [GO:0006954],
immune response [GO:0006955],
signal transduction [GO:0007165],
tyrosine phosphorylation of STAT protein [GO:0007260],
cell-cell signaling [GO:0007267],
aging [GO:0007568],
positive regulation of cell proliferation [GO:0008284],
regulation of receptor activity [GO:0010469],
skeletal muscle atrophy [GO:0014732],
hyaluronan metabolic process [GO:0030212],
positive regulation of interleukin-17 production [GO:0032740],
positive regulation of natural killer cell proliferation [GO:0032819],
positive regulation of natural killer cell differentiation [GO:0032825],
positive regulation of tissue remodeling [GO:0034105],
interleukin-15-mediated signaling pathway [GO:0035723],
positive regulation of T cell proliferation [GO:0042102],
neutrophil activation [GO:0042119],
positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531],
extrathymic T cell selection [GO:0045062],
regulation of T cell differentiation [GO:0045580],
cell maturation [GO:0048469],
lymph node development [GO:0048535],
negative regulation of smooth muscle cell proliferation [GO:0048662],
regulation of defense response to virus by host [GO:0050691],
positive regulation of inflammatory response [GO:0050729],
positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731],
positive regulation of phagocytosis [GO:0050766],
positive regulation of immune response [GO:0050778],
cellular response to vitamin D [GO:0071305],
positive regulation of protein O-linked glycosylation [GO:1904100],

Molecular Function:
cytokine activity [GO:0005125],
cytokine receptor binding [GO:0005126],
protein binding [GO:0005515],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
nucleoplasm [GO:0005654],
cytoplasm [GO:0005737],
endosome [GO:0005768],
Golgi apparatus [GO:0005794],
cytosol [GO:0005829],
cell surface [GO:0009986],
nuclear speck [GO:0016607],