AP2B1

adaptor related protein complex 2 subunit beta 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Li Fraumeni Human YES

GO terms:

Biological Process:
ventricular septum development [GO:0003281],
antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886],
low-density lipoprotein particle receptor catabolic process [GO:0032802],
low-density lipoprotein particle clearance [GO:0034383],
aorta development [GO:0035904],
positive regulation of endocytosis [GO:0045807],
ephrin receptor signaling pathway [GO:0048013],
clathrin coat assembly [GO:0048268],
regulation of defense response to virus by virus [GO:0050690],
Wnt signaling pathway, planar cell polarity pathway [GO:0060071],
coronary vasculature development [GO:0060976],
membrane organization [GO:0061024],
clathrin-dependent endocytosis [GO:0072583],
postsynaptic neurotransmitter receptor internalization [GO:0098884],
negative regulation of neuron death [GO:1901215],
positive regulation of protein localization to membrane [GO:1905477],
cardiac septum development [GO:0003279],
intracellular protein transport [GO:0006886],
endocytosis [GO:0006897],
heart development [GO:0007507],
protein transport [GO:0015031],
vesicle-mediated transport [GO:0016192],
neurotransmitter receptor internalization [GO:0099590],

Molecular Function:
signal sequence binding [GO:0005048],
protein binding [GO:0005515],
clathrin binding [GO:0030276],
clathrin adaptor activity [GO:0035615],
macromolecular complex binding [GO:0044877],
cargo receptor activity [GO:0038024],

Cellular Component:
cytosol [GO:0005829],
plasma membrane [GO:0005886],
membrane [GO:0016020],
AP-2 adaptor complex [GO:0030122],
endocytic vesicle membrane [GO:0030666],
clathrin-coated endocytic vesicle membrane [GO:0030669],
endolysosome membrane [GO:0036020],
clathrin-coated endocytic vesicle [GO:0045334],
postsynapse [GO:0098794],
glutamatergic synapse [GO:0098978],
cell [GO:0005623],
clathrin-coated pit [GO:0005905],
membrane coat [GO:0030117],
clathrin adaptor complex [GO:0030131],