AOC2

amine oxidase copper containing 2

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
28844647 BJ, WI-38, IMR-90, MRC-5, HFF-1, HCA2 Skin, Lung Human YES

Status in senescence: Down-regulated

Pubmed ID Cell line Tissue Source High-throughput
29548335 Saos-2, Li-Fraumeni Human YES

GO terms:

Biological Process:
catecholamine metabolic process [GO:0006584],
xenobiotic metabolic process [GO:0006805],
visual perception [GO:0007601],
amine metabolic process [GO:0009308],
electron transport chain [GO:0022900],
oxidation-reduction process [GO:0055114],

Molecular Function:
copper ion binding [GO:0005507],
primary amine oxidase activity [GO:0008131],
electron carrier activity [GO:0009055],
quinone binding [GO:0048038],
tryptamine:oxygen oxidoreductase (deaminating) activity [GO:0052593],
aminoacetone:oxygen oxidoreductase(deaminating) activity [GO:0052594],
aliphatic-amine oxidase activity [GO:0052595],
phenethylamine:oxygen oxidoreductase (deaminating) activity [GO:0052596],
oxidoreductase activity [GO:0016491],
metal ion binding [GO:0046872],

Cellular Component:
cytoplasm [GO:0005737],
plasma membrane [GO:0005886],