AOC1

amine oxidase copper containing 1

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
27545311 U2OS Human NO
30659069 U2OS, Hep G2, Hs68, WI-38 Human NO

GO terms:

Biological Process:
xenobiotic metabolic process [GO:0006805],
amine metabolic process [GO:0009308],
cellular response to copper ion starvation [GO:0035874],
response to drug [GO:0042493],
neutrophil degranulation [GO:0043312],
response to antibiotic [GO:0046677],
oxidation-reduction process [GO:0055114],
cellular response to copper ion [GO:0071280],
cellular response to histamine [GO:0071420],
cellular response to heparin [GO:0071504],
cellular response to azide [GO:0097185],
amiloride transport [GO:0015898],

Molecular Function:
copper ion binding [GO:0005507],
calcium ion binding [GO:0005509],
primary amine oxidase activity [GO:0008131],
drug binding [GO:0008144],
heparin binding [GO:0008201],
zinc ion binding [GO:0008270],
protein homodimerization activity [GO:0042803],
macromolecular complex binding [GO:0044877],
quinone binding [GO:0048038],
diamine oxidase activity [GO:0052597],
histamine oxidase activity [GO:0052598],
methylputrescine oxidase activity [GO:0052599],
propane-1,3-diamine oxidase activity [GO:0052600],
oxidoreductase activity [GO:0016491],
metal ion binding [GO:0046872],

Cellular Component:
extracellular region [GO:0005576],
extracellular space [GO:0005615],
peroxisome [GO:0005777],
plasma membrane [GO:0005886],
bicellular tight junction [GO:0005923],
specific granule lumen [GO:0035580],
extracellular exosome [GO:0070062],