ANXA5

annexin A5

Link to human ortholog
Link to mouse ortholog

Search for interactions with genes linked to senescence.

Status in senescence: Up-regulated

Pubmed ID Cell line Tissue Source High-throughput
22728018 Primary human lung and foreskin fibroblasts, MRC-5, WI-38, BJ, Hela U2OS Human NO

GO terms:

Biological Process:
platelet degranulation [GO:0002576],
signal transduction [GO:0007165],
blood coagulation [GO:0007596],
response to organic substance [GO:0010033],
negative regulation of blood coagulation [GO:0030195],
positive regulation of apoptotic process [GO:0043065],
negative regulation of apoptotic process [GO:0043066],
negative regulation of catalytic activity [GO:0043086],
protein homooligomerization [GO:0051260],
negative regulation of sequestering of calcium ion [GO:0051283],
response to calcium ion [GO:0051592],
calcium ion transmembrane transport [GO:0070588],
cellular response to lead ion [GO:0071284],
response to thyroid hormone [GO:0097066],
cellular response to gonadotropin-releasing hormone [GO:0097211],
regulation of flagellated sperm motility [GO:1901317],
negative regulation of prolactin secretion [GO:1902721],
hemostasis [GO:0007599],
negative regulation of coagulation [GO:0050819],

Molecular Function:
phospholipase inhibitor activity [GO:0004859],
calcium-transporting ATPase activity [GO:0005388],
calcium ion binding [GO:0005509],
protein binding [GO:0005515],
phospholipid binding [GO:0005543],
calcium-dependent phospholipid binding [GO:0005544],
heparin binding [GO:0008201],
peptide hormone binding [GO:0017046],
receptor tyrosine kinase binding [GO:0030971],
binding, bridging [GO:0060090],

Cellular Component:
extracellular region [GO:0005576],
cytoplasm [GO:0005737],
cytosol [GO:0005829],
focal adhesion [GO:0005925],
external side of plasma membrane [GO:0009897],
membrane [GO:0016020],
extracellular exosome [GO:0070062],
endothelial microparticle [GO:0072563],
extracellular space [GO:0005615],
nucleus [GO:0005634],
endoplasmic reticulum [GO:0005783],
plasma membrane [GO:0005886],
synaptic vesicle [GO:0008021],
intercalated disc [GO:0014704],
Z disc [GO:0030018],
dendrite [GO:0030425],
sarcolemma [GO:0042383],
cell projection [GO:0042995],
neuronal cell body [GO:0043025],
perikaryon [GO:0043204],
axon terminus [GO:0043679],